Biochemistry 4th Edition by Reginald Garrett, Charles Grisham

Exercise 14

How does the presence of phosphate affect the properties of nucleotides
Phosphate groups are also integral parts of nucleotides, with the second and third phosphates of a nucleotide linked through phosphoric anhydride bonds, an important distinction in terms of the metabolic role of nucleotides.
a. What property does a phosphate group have that a nucleoside lacks
b. How are phosphoric anhydride bonds useful in metabolism
c. How are phosphate anhydride bonds an advantage to energetics of polynucleotide synthesis