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Biochemistry 4th Edition by Reginald Garrett, Charles Grisham
Edition 4ISBN: 9780495109358Biochemistry 4th Edition by Reginald Garrett, Charles Grisham
Edition 4ISBN: 9780495109358 Exercise 4
Understanding the mechanism of the -ketoglutarate dehydrogenase reaction
The first step of the -ketoglutarate dehydrogenase reaction involves decarboxylation of the substrate and leaves a covalent TPP intermediate. Write a reasonable mechanism for this reaction.
The first step of the -ketoglutarate dehydrogenase reaction involves decarboxylation of the substrate and leaves a covalent TPP intermediate. Write a reasonable mechanism for this reaction.
Explanation
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The reaction involves the loss...
Biochemistry 4th Edition by Reginald Garrett, Charles Grisham
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