
Biochemistry 4th Edition by Reginald Garrett, Charles Grisham
Edition 4ISBN: 9780495109358
Biochemistry 4th Edition by Reginald Garrett, Charles Grisham
Edition 4ISBN: 9780495109358 Exercise 10
Understanding the energetics of the aconitase reaction
(Integrates with Chapter 3.) Aconitase catalyzes the citric acid cycle reaction:
citrate isocitrate
The standard free energy change, G°', for this reaction is +6.7 kJ/mol. However, the observed free energy change ( G) for this reaction in pig heart mitochondria is +0.8 kJ/mol. What is the ratio of [isocitrate]/[citrate] in these mitochondria If [isocitrate] = 0.03 mM, what is [citrate]
(Integrates with Chapter 3.) Aconitase catalyzes the citric acid cycle reaction:
citrate isocitrate
The standard free energy change, G°', for this reaction is +6.7 kJ/mol. However, the observed free energy change ( G) for this reaction in pig heart mitochondria is +0.8 kJ/mol. What is the ratio of [isocitrate]/[citrate] in these mitochondria If [isocitrate] = 0.03 mM, what is [citrate]
Explanation
The reaction is given as:
We can deter...
Biochemistry 4th Edition by Reginald Garrett, Charles Grisham
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