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Biochemistry 4th Edition by Reginald Garrett, Charles Grisham
Edition 4ISBN: 9780495109358Biochemistry 4th Edition by Reginald Garrett, Charles Grisham
Edition 4ISBN: 9780495109358 Exercise 3
Regulation of glutamine synthetase by covalent modification
Suppose at certain specific metabolite concentrations in vivo the cyclic cascade regulating E. coli glutamine synthetase has reached a dynamic equilibrium where the average state of GS adenylylation is poised at n = 6. Predict what change in n will occur if:
a. [ATP] increase.
b. P IIA / PIID increases.
c. [ -KG]/[Gln] increases.
d. [Pi] decreases.
Suppose at certain specific metabolite concentrations in vivo the cyclic cascade regulating E. coli glutamine synthetase has reached a dynamic equilibrium where the average state of GS adenylylation is poised at n = 6. Predict what change in n will occur if:
a. [ATP] increase.
b. P IIA / PIID increases.
c. [ -KG]/[Gln] increases.
d. [Pi] decreases.
Explanation
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Glutamine synthetase is a very important...
Biochemistry 4th Edition by Reginald Garrett, Charles Grisham
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