Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill

Exercise 3

A schematic structure of the subunit ot hemerythrin (an oxygen-binding protein from invertebrate animals) is shown below.
(a) It has been found that in some of the -helical regions of hemerythrin, about every third or fourth amino acid residue is a hydrophobic one. Suggest a structural reason for this finding.
(b) What would be the effect of a mutation that placed a proline residue at point A in the structure