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book Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill cover

Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill

Edition 4ISBN: 978-0138004644
book Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill cover

Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill

Edition 4ISBN: 978-0138004644
Exercise 10
In principle, an allosteric molecule could exhibit negative coopera-tivity; that is, binding of the first ligands could decrease affinity for additional ones.
(a) What would a Hill plot look like for negative cooperativity
(b) It has been noted that the KNF theory allows negative cooperativity but the MWC theory doesn't. Explain.
Explanation
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(a). In case of an allosteric molecule t...

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Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill
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