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Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill
Edition 4ISBN: 978-0138004644Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill
Edition 4ISBN: 978-0138004644 Exercise 11
In the experiments of Barrick, et al. (see Figure 7.18, page 251) it was observed that replacement of histidine by a noncovalently bonded imidazole not only reduced cooperativity but also increased the oxygen affinity of the hemoglobin. Suggest an explanation.
Explanation
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In normal hemoglobin, the oxygen binding...
Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill
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