Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill

Exercise 6

The distance actin and myosin filaments can slide past one another as a consequence of hydrolysis of one ATP molecule is variable. At high loads, the result appears to be consistent with the stroke length (about 10 nm), but at low loads much greater distances have been claimed by some researchers. Discuss this problem in terms of the model proposed in Figure 8.11.