Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill

Exercise 2

Phosphatidylserine (PS) is considered to be an intermediate in the biosynthesis of phosphatidylethanolamine (PE) in E. coli, yet PS is not found in appreciable amounts among E. coli membrane phospholipids. Because PS must be present in the membrane to serve as an intermediate, how might you explain its failure to accumulate to a significant extent What kinds of experiments could test your proposed explanation