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Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill
Edition 4ISBN: 978-0138004644Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill
Edition 4ISBN: 978-0138004644 Exercise 5
A small DNA molecule was cleaved with several different restriction nucleases, and the size of each fragment was determined by gel electrophoresis. The following data were obtained. 
(a) Is the original molecule linear or circular
(b) Draw a map of restriction sites, showing distances between sites, that is consistent with the data presented.
(c) How many additional maps are compatible with the data
(d) What would have to be done to locate the cleavage sites unambiguously with respect to each other
(a) Is the original molecule linear or circular (b) Draw a map of restriction sites, showing distances between sites, that is consistent with the data presented.
(c) How many additional maps are compatible with the data
(d) What would have to be done to locate the cleavage sites unambiguously with respect to each other
Explanation
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(a)The original molecule is circular bec...
Biochemistry 4th Edition by Christopher Mathews,Kensal van Holde, Dean Appling, Spencer Anthony Cahill
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