Molecular Biology 5th Edition by Robert Weaver

Exercise 3

Draw a T-A base pair. Based on that structure, draw a line diagram indicating the relative positions of the hydrogen bond acceptor and donor groups in the major and minor grooves. Represent the horizontal axis of the base pair by two segments of a horizontal line, and the relative horizontal positions of the hydrogen bond donors and acceptors by vertical lines. Let the lengths of the vertical lines indicate the relative vertical positions of the acceptors and donors. What relevance does this diagram have for a protein that interacts with this base pair