Math and Dosage Calculations for Health Care 3rd Edition by James Whaley, Kathryn Booth, Booth Kathryn

Exercise 86

In Exercises 20, determine if the dosage ordered is safe. If the order is safe, then find the amount to administer. Assume that the patients have impaired renal functions.
The patient: 68-year-old female, 5 ft 5 in. tall, 166 lb, CL CR of 60 mL/min. Ideal weight should be 162 lb. Ordered: Capastat 500 mg IM qd On hand: Capastat sulfate, diluted to 300 mg/mL
According to the package insert, the estimated daily dosage required to maintain a steady level of drug is 1.29 mg/kg for creatinine clearance of 0 mL/min; 2.43 mg/kg for 10 mL/min; 3.58 mg/kg for 20 mL/ min; 4.72 mg/kg for 30 mL/min; 5.87 mg/kg for 40 mL/min; 7.01 mg/kg for 50 mL/min; and 8.16 mg/kg for 60 mL/min.