
iGenetics 3rd Edition by Peter Russell
Edition 3ISBN: 978-0321569769
iGenetics 3rd Edition by Peter Russell
Edition 3ISBN: 978-0321569769 Exercise 8
The following figure shows map distances observed for genes in one chromosomal region (the open circle represents a centromere):
A new paracentric inversion bears a recessive mutation d at the D locus. Its proximal breakpoint lies between B and C , 1 mu from B , and its distal breakpoint liesbetween G and H , 1 mu from G. A heterozygote for thisinversion and the wild-type arrangement mates with a dd individual homozygous for the inversion.
a. In the absence of multiple crossovers, what is the chance that a dd offspring will have a homolog with a wild-type arrangement?
b. What type of event is required to produce a dd offspring having a homolog with a wild-type arrangement? What is the likelihood of such an event?
c. Based on your answers to (a) and (b) , how might spontaneously arising inversions contribute to the maintenance of genetic differences between subpopulations of a species?

A new paracentric inversion bears a recessive mutation d at the D locus. Its proximal breakpoint lies between B and C , 1 mu from B , and its distal breakpoint liesbetween G and H , 1 mu from G. A heterozygote for thisinversion and the wild-type arrangement mates with a dd individual homozygous for the inversion.
a. In the absence of multiple crossovers, what is the chance that a dd offspring will have a homolog with a wild-type arrangement?
b. What type of event is required to produce a dd offspring having a homolog with a wild-type arrangement? What is the likelihood of such an event?
c. Based on your answers to (a) and (b) , how might spontaneously arising inversions contribute to the maintenance of genetic differences between subpopulations of a species?
Explanation
This image depicts the chromatid after t...
iGenetics 3rd Edition by Peter Russell
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