Becker's World of the Cell 9th Edition by Lewis Kleinsmith, Jeff Hardin, Gregory Paul Bertoni

Exercise 5

The Minimal Chromosome. To enable it to be transmitted intact from one cell generation to the next, the linear DNA molecule of a eukaryotic chromosome must have appropriate nucleotide sequences making up three special lands of regions: Origins of replication (at least one), a centromere, and two telomeres. What would happen if such a chromosomal DNA molecule somehow lost:
(a)all of its origins of replication
(b)all of the DNA constituting its centromere
(c)one of its telomeres