Becker's World of the Cell 9th Edition by Lewis Kleinsmith, Jeff Hardin, Gregory Paul Bertoni

Exercise 5

Library Science. You have constructed DNA probes that you want to use to verify the quality of a genomic library and a cDNA library recently produced from a preparation of rat liver cells in your lab. Probe #1 comes from a gene that is expressed in brain cells, whereas probe #2 comes from a gene expressed in liver cells. How would you expect the frequency of clones hybridizing with each of the probes to compare when the two libraries are probed Explain your answer.