Becker's World of the Cell 9th Edition by Lewis Kleinsmith, Jeff Hardin, Gregory Paul Bertoni

Exercise 10

Down and Out. Endocannabinoids are produced by postsynaptic neurons but act on receptors (CB1 receptors)in presynaptic neurons. One type of neuron that is a target of endocannabinoids is glutamatergic neurons (that is, neurons that release glutamate as a neurotransmitter).
(a)CB1 agonists such as THC reduce calcium influx by blocking the activity of voltage-dependent calcium channels. What effect would this have on the release of glutamate
(b)Glutamate causes the membrane of postsynaptic neurons to become hyperpolarized. How would THC be expected to affect the rate of nerve impulse transmission in postsynaptic neurons that make synapses with the glutamatergic neuron