Epidemiology for Public Health Practice 5th Edition by Robert Friis,Thomas Sellers

Exercise 4

A case-control study of multiple sclerosis (MS) was conducted in which family history of MS was collected on all first- and second-degree relatives. Among the 500 cases, 16 reported an affected relative. Among the 500 age- and sex-matched controls, 8 reported an affected relative. Do these data suggest a familial component to MS?