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Molecular Biology of the Gene 7th Edition by Richard Losick, James Watson, Michael Levine, Tamara Baker, Alexander Gann
Edition 7ISBN: 9780321762436Molecular Biology of the Gene 7th Edition by Richard Losick, James Watson, Michael Levine, Tamara Baker, Alexander Gann
Edition 7ISBN: 9780321762436 Exercise 2
You want to confirm your ordering for Question 8 using a three-factor cross (cross XYZ / xyz and xyz / xyz ). Your least common recombinants are xYZ and Xyz. Does this confirm your order from Question 8? Explain why or why not.
Explanation
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Three genes X, Y, and Z are all found on the same chromosome. Each of these genes has one dominant and one recessive allele.
The map of the three genes is given below:
A three factor cross is done to check the order of the three genes.
XYZ/xyz and xyz
The crossing over occurs and the recombinants are noted. Two recombinants xYZ and Xyz are very few in number. This confirms the sequence of the three genes. These two recombinants can occur with double crossover between X and Y and again between X and Z. Since, the distance between these two genes is very less (7 m.u.) crossovers rarely occurs between X and Y.
The map of the three genes is given below:
A three factor cross is done to check the order of the three genes. XYZ/xyz and xyz
The crossing over occurs and the recombinants are noted. Two recombinants xYZ and Xyz are very few in number. This confirms the sequence of the three genes. These two recombinants can occur with double crossover between X and Y and again between X and Z. Since, the distance between these two genes is very less (7 m.u.) crossovers rarely occurs between X and Y.
Molecular Biology of the Gene 7th Edition by Richard Losick, James Watson, Michael Levine, Tamara Baker, Alexander Gann
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