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Molecular Biology of the Gene 7th Edition by Richard Losick, James Watson, Michael Levine, Tamara Baker, Alexander Gann
Edition 7ISBN: 9780321762436Molecular Biology of the Gene 7th Edition by Richard Losick, James Watson, Michael Levine, Tamara Baker, Alexander Gann
Edition 7ISBN: 9780321762436 Exercise 5
Researchers studied the interactions between proteins and DNA in more than 100 protein-DNA complexes. The table below provides a subset of the data: the distribution of single hydrogen bonds between a specific base and amino acid.
A. Explain why the researchers found no single hydrogen bonds between tryptophan and one of the DNA bases.
B. Explain why the researchers found single hydrogen bonds between glutamate and each of the DNA bases.
C. Is there a preference of arginine for one of the amino acids?
Data adapted from Luscombe et al. (2001. Nucleic Acids Res. 29: 2860-2874).
A. Explain why the researchers found no single hydrogen bonds between tryptophan and one of the DNA bases.
B. Explain why the researchers found single hydrogen bonds between glutamate and each of the DNA bases.
C. Is there a preference of arginine for one of the amino acids?
Data adapted from Luscombe et al. (2001. Nucleic Acids Res. 29: 2860-2874).
Explanation
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Molecular Biology of the Gene 7th Edition by Richard Losick, James Watson, Michael Levine, Tamara Baker, Alexander Gann
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