Molecular Biology of the Gene 7th Edition by Richard Losick, James Watson, Michael Levine, Tamara Baker, Alexander Gann

Exercise 13

Consider a loss-of-function mutant in the nucleotide excision repair and translesion synthesis pathway. Predict the level of DNA damage, percent survival, and level of mutagenesis relative to wild type for each mutant after exposure to UV light. In the table below, fill each blank with increase, decrease, or stay the same.