Molecular Biology of the Gene 7th Edition by Richard Losick, James Watson, Michael Levine, Tamara Baker, Alexander Gann

Exercise 14

You discover a new operon that is regulated by a repressor in a prokaryotic species. Assuming the represso binds an operator site, design an in vitro experiment to identify the specific region where the repressor binds DNA under conditions similar to those normally found for repression in the cell.