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Molecular Biology Of The Cell 6th Edition by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Edition 6ISBN: 978-0815345244Molecular Biology Of The Cell 6th Edition by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
Edition 6ISBN: 978-0815345244 Exercise 9
Normally, the flow of electrons to 
is tightly linked to the production of ATP via the electrochemical gradient. If ATP synthase is inhibited, for example, elec- trons do not flow down the electron-transport chain and respiration ceases. Since the 1940s, several substances- such as 2,4-dinitrophenol-have been known to uncou- ple electron flow from ATP synthesis. Dinitrophenol was once prescribed as a diet drug to aid in weight loss. How would an uncoupler of oxidative phosphorylation pro- mote weight loss? Why do you suppose dinitrophenol is no longer prescribed?
is tightly linked to the production of ATP via the electrochemical gradient. If ATP synthase is inhibited, for example, elec- trons do not flow down the electron-transport chain and respiration ceases. Since the 1940s, several substances- such as 2,4-dinitrophenol-have been known to uncou- ple electron flow from ATP synthesis. Dinitrophenol was once prescribed as a diet drug to aid in weight loss. How would an uncoupler of oxidative phosphorylation pro- mote weight loss? Why do you suppose dinitrophenol is no longer prescribed?Explanation
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The pH within actively respiring mitocho...
Molecular Biology Of The Cell 6th Edition by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
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