Molecular Biology Of The Cell 6th Edition by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter

Exercise 1

Which statements are true? explain why or why not.
-7 The Wnt planar polarity signaling pathway nor- mally ensures that each wing cell in Drosophila has a sin- gle hair. Overexpression of the Frizzled gene from a heat- shock promoter causes multiple hairs to grow from many cells (Figure Q15-5A). This phenotype is suppressed if is combined with a heterozygous deletion of the Dishevelled gene (Figure Q15-5B). Do these results allow you to order the action of Frizzled and Dishevelled in the signaling pathway? If so, what is the order? Explain your reasoning.