Molecular Biology Of The Cell 6th Edition by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter

Exercise 3

1 John Snow is widely regarded as the father of mod- ern epidemiology. Most famously, he investigated an out- break of cholera in London in 1854 that killed more than 600 victims before it was finished. Snow recorded where the victims lived, and plotted the data on a map, along with the locations of the water pumps that served as the source of water for the public (Figure Q23-2). He concluded that the disease was most likely spread in the water, although he could find nothing suspicious-looking in it. His conclu- sion ran counter to the then-current belief that cholera was from "miasmas" in bad air. Very few believed his theory during the next 50 years, with the "bad air" theory persist- ing until at least 1901. What do you suppose Snow saw in the data that led him to his conclusion? Why do you think most scientists remained skeptical for so long?