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book Molecular Biology Of The Cell 6th Edition by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter cover

Molecular Biology Of The Cell 6th Edition by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter

Edition 6ISBN: 978-0815345244
book Molecular Biology Of The Cell 6th Edition by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter cover

Molecular Biology Of The Cell 6th Edition by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter

Edition 6ISBN: 978-0815345244
Exercise 10
Based on its sequence similarity to Apobec1, which deaminates Cs to Us in RNA, activation-induced deaminase (AID) was originally proposed to work on RN a. But definitive experiments in
A. Which part of the viral protein gives rise to the peptide that is recognized by the clone of cytotoxic T cells? Why do not all viral peptides sensitize the target cells for lysis by the cytotoxic T cells?
B. It is thought the MHC molecules come to the cell surface with peptides already bound. If that is so, how do you imagine that these experiments worked? Based on its sequence similarity to Apobec1, which deaminates Cs to Us in RNA, activation-induced deaminase (AID) was originally proposed to work on RN a. But definitive experiments in A. Which part of the viral protein gives rise to the peptide that is recognized by the clone of cytotoxic T cells? Why do not all viral peptides sensitize the target cells for lysis by the cytotoxic T cells? B. It is thought the MHC molecules come to the cell surface with peptides already bound. If that is so, how do you imagine that these experiments worked?
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T-cells (thymocytes) are a component of ...

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Molecular Biology Of The Cell 6th Edition by Bruce Alberts, Alexander Johnson, Julian Lewis, David Morgan, Martin Raff, Keith Roberts, Peter Walter
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