Biomedical Engineering: Bridging Medicine and Technology 1st Edition by Veronique Tran,Mark Saltzman

Exercise 8

The Michaelis-Menten equation (Equation 4.2) provides information about enzyme kinetics.
a.
a. Draw a schematic of a plot of the Michaelis-Menten equation for a particular enzyme substrate pair. Be sure to label the x- and y-axes. Indicate the Vmax and Km values on the graph.
b. On your plot, also show the kinetic curve (V0 vs. [S]) for the same enzyme with a substrate for which the enzyme has a lower affinity than the substrate in
c. On your plot, also show the kinetic curve for the situation described in (a) but with an increased quantity of enzyme. Assume that the enzyme concentration is two times higher than in (a).