Biomedical Engineering: Bridging Medicine and Technology 1st Edition by Veronique Tran,Mark Saltzman

Question

Biomedical Engineering: Bridging Medicine and Technology 1st Edition by Veronique Tran,Mark Saltzman

Edition 1ISBN: 9780521840996

Biomedical Engineering: Bridging Medicine and Technology 1st Edition by Veronique Tran,Mark Saltzman

Edition 1ISBN: 9780521840996

Exercise 1

An equilibrium dialysis experiment was performed to characterize the bind- ing afﬁnity of a mouse IgG or human IgG antibody for an antigen, GAD65. The association constant for the monoclonal mouse IgG is $An equilibrium dialysis experiment was performed to characterize the bind- ing afﬁnity of a mouse IgG or human IgG antibody for an antigen, GAD65. The association constant for the monoclonal mouse IgG is and for a human IgG is a. Calculate the dissociation constant for each antibody. Which antibody has a higher binding afﬁnity for GAD65? Explain. b. For a GAD65 concentration of 0.7 nM, calculate the fraction of free Ab sites for each antibody.$ and for a human IgG is $An equilibrium dialysis experiment was performed to characterize the bind- ing afﬁnity of a mouse IgG or human IgG antibody for an antigen, GAD65. The association constant for the monoclonal mouse IgG is and for a human IgG is a. Calculate the dissociation constant for each antibody. Which antibody has a higher binding afﬁnity for GAD65? Explain. b. For a GAD65 concentration of 0.7 nM, calculate the fraction of free Ab sites for each antibody.$
a. Calculate the dissociation constant for each antibody. Which antibody has a higher binding afﬁnity for GAD65? Explain.
b. For a GAD65 concentration of 0.7 nM, calculate the fraction of free Ab sites for each antibody. $An equilibrium dialysis experiment was performed to characterize the bind- ing afﬁnity of a mouse IgG or human IgG antibody for an antigen, GAD65. The association constant for the monoclonal mouse IgG is and for a human IgG is a. Calculate the dissociation constant for each antibody. Which antibody has a higher binding afﬁnity for GAD65? Explain. b. For a GAD65 concentration of 0.7 nM, calculate the fraction of free Ab sites for each antibody.$

Explanation

Verified

a) In biochemistry or pharmacology, diss...