Biomedical Engineering: Bridging Medicine and Technology 1st Edition by Veronique Tran,Mark Saltzman

Exercise 14

A schematic diagram of the Ocusert?R system for delivery of pilocarpine
is shown in the accompanying figure. Using your knowledge of diffusion
through polymer membranes (from Chapter 2), derive an equation that will
predict the rate of drug release (M, mg/h) from the following parameters:
drug concentration in the reservoir (cp, mg/mL), thickness of the membranes
(cm), diffusion coefficient of drug in the membrane (DA,cm2/s), and surface
area of the device (A,cm2).