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Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
Edition 2ISBN: 9780130819086Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
Edition 2ISBN: 9780130819086 Exercise 10
It is desired to model the growth of an individual bacterium. The cell transports S₁ into the
cell enzymatically, and the permease is subject to product inhibition. S₁ is converted into pre-
cursors, P, that are converted finally into the macromolecular portion of the cell, M. The cata-
lyst of all reactions is M.
(1)
(per unit surface area)where S* = outside concentration of S
(2)
(3a) 
(3b) 
The dry weight of the cell is T and is equal to
(4)
where 
cell density and V = cell volume
Write the equations and define all symbols necessary to describe the changes in S₁, P, M, and
T within the cell. Remember that the cell volume is always changing.
cell enzymatically, and the permease is subject to product inhibition. S₁ is converted into pre-
cursors, P, that are converted finally into the macromolecular portion of the cell, M. The cata-
lyst of all reactions is M.
(1)
(per unit surface area)where S* = outside concentration of S(2)
(3a) (3b) The dry weight of the cell is T and is equal to(4)
where cell density and V = cell volumeWrite the equations and define all symbols necessary to describe the changes in S₁, P, M, and
T within the cell. Remember that the cell volume is always changing.
Explanation
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The cell transports S 1 enzymatically in...
Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
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