Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler

Exercise 7

Consider a 1000-l CSTR in which biomass is being produced with glucose as the substrate.
The microbial system follows a Monod relationship with (an unusu-
ally high value), and the yield factor biomass/g substrate consumed. If normal
operation is with a sterile feed containing 10 g/l glucose at a rate of 100 l/h:
a. What is the specific biomass production rate (g/l-h) at steady state?
b.
b. If recycle is used with a recycle stream of 10 l/h and a recycle biomass concentration five
times as large as that in the reactor exit, what would be the new specific biomass produc-
tion rate?
c. Explain any difference between the values found in parts a and