
Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
Edition 2ISBN: 9780130819086
Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
Edition 2ISBN: 9780130819086 Exercise 11
Given the following information, calculate the probability of forming a plasmid-free cell due
to random segregation for a cell with 50 plasmid monomer equivalents:
a. 40% of the total plasmid DNA is in dimers and 16% in tetramers.
b. The distribution of copy numbers per cell is as follows, assuming monomers only:

to random segregation for a cell with 50 plasmid monomer equivalents:
a. 40% of the total plasmid DNA is in dimers and 16% in tetramers.
b. The distribution of copy numbers per cell is as follows, assuming monomers only:

Explanation
a) The value P for a cell with the equiv...
Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
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