Deck 21: Extemporaneous Prescription Compounding

Question 1

What is the advantage of a conical graduate?

A) more accurate
B) calibrated in metric only
C) easier to clean
D) easier to read

Answer 1

easier to clean

Question 2

Manufacturing of prescription products for resale to pharmacies is regulated by the

A) Drug Enforcement Administration (DEA)
B) American Pharmacists Associations (APhA)
C) United States Pharmacopeia (USP)
D) Food and Drug Administration (FDA)

Answer 2

Food and Drug Administration (FDA)

Question 3

Which balance is NOT appropriate for prescription compounding?

A) class A prescription balance
B) electronic balance
C) counterbalance
D) none of the above

Answer 3

counterbalance

Question 4

Which type of measuring device is most accurate for volumes greater than 1.5 mL?

A) conical graduate
B) cylindrical graduate
C) pipette
D) all above are equally accurate

Question 5

The smallest size graduate available is

A) 1 mL
B) 2 mL
C) 5 mL
D) 10 mL

Question 6

The first step in adding a salt to a syrup is to add

A) salt to a few milliliters of water
B) salt to a few milliliters of syrup
C) few milliliters of water to the syrup
D) salt to the final syrup solution

Question 7

The maximum amount that can be weighed out with a Class A balance is

A) 10 g
B) 50 g
C) 100 g
D) 120 g

Question 8

Mortars and pestles are usually made of all the following, EXCEPT

A) glass
B) wedgewood
C) ceramic
D) porcelain

Question 9

Unlike compounded solutions, suspensions

A) are difficult to compound
B) should never be shaken
C) always need to be filtered
D) have problematic physical stability once compounded

Question 10

When measuring out a liquid, it is good practice to

A) select a container that will be half full when measuring
B) view the measurement by looking at eye level to the surface
C) measure a volume that is at least 20% of the capacity of the graduate
D) all the above

Question 11

When measuring out a liquid in a graduate, the upper surface of the liquid is called

A) meniscus
B) quarter-moon-shaped body
C) liquid top
D) both a and b

Question 12

Why are balance weights usually made of a metal such as brass?

A) Metal is more dense.
B) Metal is corrosion resistant.
C) Metal is cheaper.
D) Metal is softer.

Question 13

Which balance is more appropriate for weighing out bulk quantities of products?

A) class A prescription balance
B) electronic balance
C) counterbalance
D) none of the above

Question 14

Spatulas are usually made of

A) plastic
B) stainless steel
C) hard rubber
D) all the above

Question 15

When compounding solutions, the drug should be dissolved in the

A) solvent in which it is more soluble
B) solvent in which it is least soluble
C) final solution before it is dispensed
D) least amount of solvent possible

Question 16

Compounding slabs are also known as

A) glass slabs
B) hard slabs
C) cream slabs
D) ointment slabs

Question 17

Balance weights should only be handled with

A) latex gloves
B) forceps
C) spatula
D) none of the above

Question 18

The type of mortar and pestle that has the advantage of being nonporous and nonstaining is

A) glass
B) wedgewood
C) ceramic
D) porcelain

Question 19

Class A balances have a sensitivity requirement of

A) 1 mg
B) 2 mg
C) 3 mg
D) 6 mg

Question 20

When compounding a solution, which form of the drug should be used?

A) salt form
B) free-acid form
C) free-base form
D) none of the above

Question 21

Which piece of equipment is used to remove seals placed onto vials?

A) decapper
B) crimper
C) hot plate
D) heat gun

Question 22

Preparation of sterile products requires

A) special training and skills
B) pharmacy technician certification
C) compounding pharmacist certification
D) all of the above

Question 23

When reconstituting dry powders of parenteral drugs, it is important to know the

A) correct diluent
B) color of the powder
C) manufacturer
D) both a and c

Question 24

When mixing two or more powders, you should

A) pulverize them together to the same particle size
B) pulverize them separately to the same particle size
C) mix them with the heavier powder on the bottom
D) both b and c

Question 25

Ointments are considered

A) oil based in nature
B) water based in nature
C) semisolid dosage form
D) both a and c

Question 26

Which device is used to shrink bands onto vials?

A) hot plate
B) heat sealer
C) heat gun
D) crimper

Question 27

____________________ are the most frequent form of compounded medications.

Question 28

A solid dosage form in which the drug is enclosed within either a hard or soft soluble container or shell is called a(n) ____________________.

Question 29

The largest capsule size that should be given orally to patients is

A) number 0
B) number 00
C) number 000
D) number 5

Question 30

An example of a drug that is applied topically but is intended for systemic absorption into the body is

A) hydrocortisone
B) nitroglycerin
C) benzocaine
D) diphenhydramine

Question 31

An empty ____________________ is the weight of an empty capsule used to compare to the full capsule on a balance.

Question 32

Which piece of equipment is designed for mixing and melting substances?

A) beaker
B) graduate
C) mortar
D) auto-pipette

Question 33

Which type of base is a water-miscible base often used in vaginal and rectal suppositories?

A) cocoa butter
B) polyethylene glycol
C) Carbowax
D) glycerinated gelatin

Question 34

____________________ are the standards of practice used in the pharmaceutical industry and are regulated by the FDA.

Question 35

A two-pan device that may be used for weighing small amounts of drugs (not more than 120 grams) is called a(n)

A) counterbalance
B) class A prescription balance
C) electronic counterbalance
D) electronic balance

Question 36

Tablet molds are commonly made of

A) glass
B) paper
C) plastic
D) metal

Question 37

Which type of base is used most commonly for rectal suppositories?

A) cocoa butter
B) polyethylene glycol
C) Carbowax
D) glycerinated gelatin

Question 38

Sterility of compounded products can be achieved through the following methods, EXCEPT

A) freezing
B) filtration
C) heat
D) gas

Question 39

The preparation, mixing, assembling, packaging, and labeling of a drug based on a prescription is called ____________________.

Question 40

The minimum amount you should measure with a 100 mL graduated cylinder is

A) 5 mL
B) 10 mL
C) 20 mL
D) 50 mL

Question 41

Solid, small, and usually cylindrically molded or compressed tablets are called tablet ____________________.

Question 43

Describe tablet molds.

Question 44

To grind into a smooth substance with moisture is to ____________________.

Question 45

Explain the procedure for properly measuring a volume using a graduated cylinder. How is the measurement read accurately?

Question 46

To ____________________ is to reduce to a fine powder by friction.

Question 47

What are four general rules to consider when compounding solutions?

Question 48

A pipette can be used for ____________________ of volumes of liquids that are less than 1.5 mL.

Question 49

List four examples of semisolid forms and explain the characteristics of ointments and creams.

Question 50

Describe the minimum requirements for compounding intravenous admixtures appropriately. In what practice setting is this usually done?

Question 51

The term "____________________" is defined as a sweetened liquid containing alcohol and water.