Deck 6: Overview of Drug Analysis
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Deck 6: Overview of Drug Analysis
1
In general, drugs are regulated based on
A) cost
B) complexity of synthesis
C) potential harm to the person and society
D) toxicity
E) none of the above
A) cost
B) complexity of synthesis
C) potential harm to the person and society
D) toxicity
E) none of the above
C
2
In the US, regulated drugs of abuse are defined by the
A) Controlled Substances Act and addendums
B) Dangerous Precursors Law
C) Harrison Narcotics Act
D) Marijuana Tax Act
E) none of the above
A) Controlled Substances Act and addendums
B) Dangerous Precursors Law
C) Harrison Narcotics Act
D) Marijuana Tax Act
E) none of the above
A
3
According to the CSA, which of the following drugs are available by prescription?
A) Schedule I
B) Schedule V
C) Schedules I and V
D) Schedule II, III, IV, and V
E) none of the above
A) Schedule I
B) Schedule V
C) Schedules I and V
D) Schedule II, III, IV, and V
E) none of the above
D
4
Why are precursor chemicals regulated? Because
A) they can be addictive
B) they are easily converted into illegal substances
C) they cause intoxication
D) they are highly toxic
E) none of the above
A) they can be addictive
B) they are easily converted into illegal substances
C) they cause intoxication
D) they are highly toxic
E) none of the above
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5
Substances that slow brain activity and support relaxation and sleep are classified as
A) cannabinoids
B) dissociatives
C) hallucinogens
D) opiates/opioids
E) stimulants
F) sedatives/hypnotics
G) more than one of the above
H) none of the above
A) cannabinoids
B) dissociatives
C) hallucinogens
D) opiates/opioids
E) stimulants
F) sedatives/hypnotics
G) more than one of the above
H) none of the above
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6
Substances that cause a sense of separation from self, disconnectedness, and an anesthetic effect are
A) cannabinoids
B) dissociatives
C) hallucinogens
D) opiates/opioids
E) stimulants
F) sedatives/hypnotics
G) more than one of the above
H) none of the above
A) cannabinoids
B) dissociatives
C) hallucinogens
D) opiates/opioids
E) stimulants
F) sedatives/hypnotics
G) more than one of the above
H) none of the above
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7
Drugs related to morphine would fall into which category?
A) cannabinoids
B) dissociatives
C) hallucinogens
D) opiates/opioids
E) stimulants
F) sedatives/hypnotics
G) more than one of the above
H) none of the above
A) cannabinoids
B) dissociatives
C) hallucinogens
D) opiates/opioids
E) stimulants
F) sedatives/hypnotics
G) more than one of the above
H) none of the above
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8
A new drug causes your big toe to swell. How would this drug be categorized?
A) cannabinoids
B) dissociatives
C) hallucinogens
D) opiates/opioids
E) stimulants
F) sedatives/hypnotics
G) more than one of the above
H) none of the above
A) cannabinoids
B) dissociatives
C) hallucinogens
D) opiates/opioids
E) stimulants
F) sedatives/hypnotics
G) more than one of the above
H) none of the above
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9
Caffeine would be classified as which of the following?
A) cannabinoids
B) dissociatives
C) hallucinogens
D) opiates/opioids
E) stimulants
F) sedatives/hypnotics
G) more than one of the above
H) none of the above
A) cannabinoids
B) dissociatives
C) hallucinogens
D) opiates/opioids
E) stimulants
F) sedatives/hypnotics
G) more than one of the above
H) none of the above
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10
A person takes a drug and has a meaningful conversation with a purple dinosaur. How would this drug be classified?
A) cannabinoids
B) dissociatives
C) hallucinogens
D) opiates/opioids
E) stimulants
F) sedatives/hypnotics
G) more than one of the above
H) none of the above
A) cannabinoids
B) dissociatives
C) hallucinogens
D) opiates/opioids
E) stimulants
F) sedatives/hypnotics
G) more than one of the above
H) none of the above
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11
Pharmaceutical identifiers are
A) a table of currently abused commercial drugs maintained by the DEA
B) physical descriptors of a commercial form of a drug
C) tests in the analytical scheme used for seized drug analysis
D) Taggants placed in commercial pills for identification purposes
E) none of the above
A) a table of currently abused commercial drugs maintained by the DEA
B) physical descriptors of a commercial form of a drug
C) tests in the analytical scheme used for seized drug analysis
D) Taggants placed in commercial pills for identification purposes
E) none of the above
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12
Pseudoepherine is a/an ________ for the clandestine synthesis of methamphetamine
A) immediate precursor
B) distant precursor
C) ancillary substance
D) solvent substitue
E) none of the above
A) immediate precursor
B) distant precursor
C) ancillary substance
D) solvent substitue
E) none of the above
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13
A sample of cocaine is found to contain caffeine. The caffeine is a/an
A) diluent
B) desiccant
C) adulterant
D) precursor
E) none of the above
A) diluent
B) desiccant
C) adulterant
D) precursor
E) none of the above
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14
Which of the following is/are pharmacologically active?
A) diluents
B) desiccant
C) adulterant
D) precursor
E) none of the above
A) diluents
B) desiccant
C) adulterant
D) precursor
E) none of the above
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15
Cornstarch and lactose are found in a sample that also contains ~10% heroin. These two components are
A) diluents
B) desiccants
C) adulterants
D) precursors
E) none of the above
A) diluents
B) desiccants
C) adulterants
D) precursors
E) none of the above
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16
Which of the following are not pharmacologically active?
A) diluents
B) desiccants
C) adulterants
D) precursors
E) none of the above
A) diluents
B) desiccants
C) adulterants
D) precursors
E) none of the above
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17
Analysis of cutting agents and adulterants are used
A) to provide additional information for an investigation
B) to assess the severity of the crime involved
C) to establish how a drug was synthesized
D) all of the above
E) none of the above
A) to provide additional information for an investigation
B) to assess the severity of the crime involved
C) to establish how a drug was synthesized
D) all of the above
E) none of the above
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18
The clandestine synthesis of methamphetamine from P2P or pseudoephedrine involves what chemical process?
A) oxidative additions
B) reductive oxidation
C) reductive amination
D) a Grignard reaction
E) none of the above
A) oxidative additions
B) reductive oxidation
C) reductive amination
D) a Grignard reaction
E) none of the above
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19
Profiling of drug samples can involve which type(s) of analysis?
A) IRMS
B) Elemental analysis
C) Trace solvent analysis
D) All of the above
E) none of the above
A) IRMS
B) Elemental analysis
C) Trace solvent analysis
D) All of the above
E) none of the above
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20
The group of tests used to characterize exhibits of seized drugs is called the
A) Standard operating procedure (SOP)
B) analytical scheme
C) identification
D) quantitation
E) none of the above
A) Standard operating procedure (SOP)
B) analytical scheme
C) identification
D) quantitation
E) none of the above
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21
An analytical scheme begins with
A) the most specific test
B) GC-MS
C) FTIR
D) the least specific test
E) none of the above
A) the most specific test
B) GC-MS
C) FTIR
D) the least specific test
E) none of the above
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22
Tests that are based on color changes are used for
A) definitive identification in the field
B) rough quantitation
C) identification of diluents and adulterants in the lab
D) identification of diluents and adulterants in the field
E) none of the above
A) definitive identification in the field
B) rough quantitation
C) identification of diluents and adulterants in the lab
D) identification of diluents and adulterants in the field
E) none of the above
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23
A sample of a brown powder produces a strong purple color suggesting the presence of an opiate or opioid. The mass spectrum from GC-MS testing shows the presence of a compound related to methamphetamine. This is an example of data that is
A) internally consistent
B) reasonable, defensible, and fit for purpose
C) inconsistent
D) useless
E) none of the above
A) internally consistent
B) reasonable, defensible, and fit for purpose
C) inconsistent
D) useless
E) none of the above
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24
What are the two primary mechanisms of color test reagents?
A) changes in d-orbitals in transition metals and increasing conjugation
B) changes of atomic orbitals into molecular orbitals
C) decreasing conjugation and degenerate d-orbitals
D) transition metal conversions and molecular orbital inversions
E) none of the above
A) changes in d-orbitals in transition metals and increasing conjugation
B) changes of atomic orbitals into molecular orbitals
C) decreasing conjugation and degenerate d-orbitals
D) transition metal conversions and molecular orbital inversions
E) none of the above
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25
A substance that absorbs light in the red region of the VIS spectrum will appear
A) red
B) blue
C) green
D) yellow
E) none of the above
A) red
B) blue
C) green
D) yellow
E) none of the above
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26
How does the Marquis reagent work to generate a colored product?
A) d-orbital splitting
B) increased conjugation and dye formation
C) sp3 hybridization
D) nπ inversions
E) none of the above
A) d-orbital splitting
B) increased conjugation and dye formation
C) sp3 hybridization
D) nπ inversions
E) none of the above
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27
How does the Marquis reagent work to generate a colored product?
A) d-orbital splitting
B) increased conjugation and dye formation
C) sp3 hybridization
D) nπ inversions
E) none of the above
A) d-orbital splitting
B) increased conjugation and dye formation
C) sp3 hybridization
D) nπ inversions
E) none of the above
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