Deck 1: Organization and Function of the Nervous System

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Question
The three major classes of neurons are

A) motor, sensory, and interneurons.
B) efferent, afferent, and glia.
C) motor, efferent, and afferent.
D) glia, interneurons, and motor.
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Question
The nucleus of a neuron resides within the

A) terminal button.
B) axon.
C) cell body.
D) dendrites.
Question
The axon hillock is located

A) at a cell's terminal button.
B) at gaps in a cell's myelin.
C) where the axon leaves the cell body.
D) where dendrites connect to the cell body.
Question
Myelin serves to

A) increase the speed of conduction along the axon.
B) insulate a cell's axon from the electrical activity of adjacent axons.
C) synthesize and store neurotransmitter substances.
D) Both a and b are correct
Question
Neurotransmitters are stored and released from a cell's

A) terminal button.
B) node of Ranvier.
C) cell body.
D) axon hillock.
Question
The pressures acting on charged ions include ________ and ________ pressures.

A) hydrostatic; electrostatic
B) diffusion; hydrostatic
C) diffusion; electrostatic
D) diffusion; glucostatic
Question
A neuron's resting membrane potential is caused by

A) sodium ions.
B) a disequilibrium of positive and negatively charged ions inside and outside the axon.
C) a high concentration of sodium inside the cell.
D) potassium ions.
Question
The resting membrane potential has a charge of about ________ millivolts.

A) 0
B) +100
C) −70
D) −55
Question
The resting membrane potential is maintained because

A) potassium ions cannot cross through the cell membrane to the outside.
B) sodium ions cannot cross to the inside of the cell membrane.
C) there is no pressure acting on sodium ions.
D) there is no pressure acting on potassium ions.
Question
Potassium is said to be at equilibrium during a resting potential because

A) electrostatic pressure forcing it in equals the diffusion pressure forcing it out.
B) diffusion pressure forcing it in equals the electrostatic pressure forcing it out.
C) hydrostatic pressure forcing it in equals the electrostatic pressure forcing it out.
D) it is equally concentrated inside and outside the cell.
Question
Changes in the voltage of a cell that vary depending on the strength of stimulation are referred to as

A) action potentials.
B) depolarization.
C) hyperpolarization.
D) graded potentials.
Question
When an axon is depolarized to approximately ________ millivolts, an action potential is initiated.

A) −55
B) −70
C) 0
D) +30
Question
Ion channels for sodium ions open when the membrane is ________ to about ________ millivolts.

A) depolarized; −55
B) polarized; −70
C) charged; +30
D) depolarized; 0
Question
The initiation of an action potential is a consequence of an ________ of ________ ions.

A) influx; potassium
B) efflux; chlorine
C) influx; sodium
D) All of the above are correct
Question
During an action potential, the membrane voltage changes from ________ to about ________ millivolts on the inside relative to the outside.

A) −70; 0
B) 0; +50
C) −70; +30
D) −70; +55
Question
Local anesthetics such as lidocaine work by

A) preventing the release of neurotransmitters signaling pain messages.
B) blocking sodium channels so an action potential cannot occur.
C) preventing cells from receiving signals from pain-transmitting neurons.
D) blocking receptor sites for pain-signaling neurotransmitters.
Question
Myelin is made up of ________ in the central nervous system.

A) fat cells
B) Schwann cells
C) oligodendrocytes
D) astrocytes
Question
Myelin is made up of ________ in the peripheral nervous system.

A) fat cells
B) Schwann cells
C) oligodendrocytes
D) astrocytes
Question
Gaps in myelin surrounding an axon are referred to as

A) receptors.
B) demyelination.
C) nodes of Ranvier.
D) synapses.
Question
The total amount of neurotransmitter released during an action potential depends on

A) how much sodium enters the terminal button.
B) how much calcium is ejected from the terminal button.
C) regulatory proteins that contain the neurotransmitter substance.
D) how much calcium enters the terminal button.
Question
Once released into the synaptic gap, neurotransmitter substances

A) bind to receptor sites on both pre- and postsynaptic sites.
B) are degraded by a breakdown enzyme.
C) are returned to the transmitting cell via reuptake.
D) All of the above are correct
Question
Receptor proteins that directly control either the opening or closing of specific ion channels are referred to as ________ receptors.

A) ionotropic
B) metabotropic
C) postsynaptic
D) presynaptic
Question
Receptor proteins that indirectly open or close ion channels through the activation of a second messenger are referred to as ________ receptors.

A) ionotropic
B) metabotropic
C) postsynaptic
D) presynaptic
Question
Which of the following is an example of a second messenger?

A) Sodium
B) A G-protein
C) Acetylcholine
D) Cyclic adenosine monophosphate
Question
Proteins on the presynaptic terminal that transport neurotransmitter substances back into the terminal button are referred to as

A) G-proteins.
B) reuptake transporters.
C) autoreceptors.
D) metabotropic receptors.
Question
Receptors on the presynaptic terminal that regulate neurotransmitter synthesis and storage are referred to as

A) heteroreceptors.
B) autoreceptors.
C) metabotropic receptors.
D) Both a and b are correct
Question
The main difference between autoreceptors and heteroreceptors is that

A) heteroreceptors are activated by a different neuron and neurotransmitter, whereas autoreceptors are activated by the neuron they regulate.
B) heteroreceptors are postsynaptic, whereas autoreceptors are presynaptic.
C) heteroreceptors are metabotropic, whereas autoreceptors are ionotropic.
D) heteroreceptors are excitatory, whereas autoreceptors are inhibitory.
Question
Which of the following is NOT a criterion for a substance to meet the definition of a neurotransmitter?

A) It must be synthesized and stored in the presynaptic neuron.
B) It must cause a postsynaptic effect after it interacts with a receptor.
C) It must be taken up intact by the transmitting neuron.
D) It must have some mechanism for its degradation or reuptake.
Question
Otto Loewi received the Nobel Prize in 1936 for his discovery of

A) dopamine.
B) norepinephrine.
C) serotonin.
D) acetylcholine.
Question
The neurotransmitter that activates all neuromuscular synapses is called

A) norepinephrine.
B) acetylcholine.
C) dopamine.
D) muscarine.
Question
The neurotransmitter of the mesolimbic system is called

A) norepinephrine.
B) serotonin.
C) adenosine.
D) dopamine.
Question
The neurotransmitter involved in emotional behavior, arousal, and sleep that is derived from the amino acid tryptophan is called

A) dopamine.
B) norepinephrine.
C) serotonin.
D) acetylcholine.
Question
The most abundant excitatory neurotransmitter is called

A) GABA.
B) serotonin.
C) norepinephrine.
D) glutamate.
Question
The glutamate receptor that has been implicated as a mechanism for long-term potentiation is called

A) NMDA.
B) metabotropic.
C) kainate.
D) AMPA.
Question
Alcohol binds to a specific receptor site on the ________ receptor complex.

A) NMDA
B) GABA
C) dopamine
D) norepinephrine
Question
The neurotransmitter that transmits pain signals in the spinal cord is called

A) serotonin.
B) glycine.
C) Substance P.
D) nonrepinephrine.
Question
Anatomical sections through the brain along the axis from front to back are called ________ sections.

A) coronal
B) horizontal
C) sagittal
D) oblique
Question
The respiratory center of the brain is located in the

A) medulla.
B) pons.
C) midbrain.
D) cerebellum.
Question
Damage to the ________ might lead to jerky, uncoordinated movements.

A) medulla
B) pons
C) midbrain
D) cerebellum
Question
A system of neurons originating deep in the brainstem which controls arousal, consciousness, and alertness is the ________ system.

A) mesolimbic
B) reticular activating
C) striatal
D) somatosensory
Question
The mesolimbic-cortical system originates in the ________ and projects dopamine containing neurons to the ________.

A) nucleus accumbens; frontal cortex
B) septum; prefrontal cortex
C) ventral tegmental area; frontal cortex
D) ventral tegmental area; nucleus accumbens
Question
The ________ undergoes considerable degeneration with prolonged periods of stress, schizophrenia, or posttraumatic stress disorder.

A) hypothalamus
B) hippocampus
C) thalamus
D) basal ganglia
Question
The ventromedial nucleus, lateral nucleus, preoptic nucleus, and paraventricular nucleus are all parts of the

A) hypothalamus.
B) thalamus.
C) basal ganglia.
D) mesolimbic system.
Question
The ________ controls most sensory input to the cortex and is involved in regulating attention and arousal.

A) hypothalamus
B) basal ganglia
C) medulla
D) thalamus
Question
Which of the following is NOT part of the basal ganglia?

A) Caudate nucleus
B) Putamen
C) Substantia nigra
D) Nucleus accumbens
Question
Which of the following structures of the brain is affected by Parkinson's disease?

A) Thalamus
B) Substantia nigra
C) Nucleus accumbens
D) Hippocampus
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Deck 1: Organization and Function of the Nervous System
1
The three major classes of neurons are

A) motor, sensory, and interneurons.
B) efferent, afferent, and glia.
C) motor, efferent, and afferent.
D) glia, interneurons, and motor.
A
2
The nucleus of a neuron resides within the

A) terminal button.
B) axon.
C) cell body.
D) dendrites.
C
3
The axon hillock is located

A) at a cell's terminal button.
B) at gaps in a cell's myelin.
C) where the axon leaves the cell body.
D) where dendrites connect to the cell body.
C
4
Myelin serves to

A) increase the speed of conduction along the axon.
B) insulate a cell's axon from the electrical activity of adjacent axons.
C) synthesize and store neurotransmitter substances.
D) Both a and b are correct
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k this deck
5
Neurotransmitters are stored and released from a cell's

A) terminal button.
B) node of Ranvier.
C) cell body.
D) axon hillock.
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Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
6
The pressures acting on charged ions include ________ and ________ pressures.

A) hydrostatic; electrostatic
B) diffusion; hydrostatic
C) diffusion; electrostatic
D) diffusion; glucostatic
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
7
A neuron's resting membrane potential is caused by

A) sodium ions.
B) a disequilibrium of positive and negatively charged ions inside and outside the axon.
C) a high concentration of sodium inside the cell.
D) potassium ions.
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k this deck
8
The resting membrane potential has a charge of about ________ millivolts.

A) 0
B) +100
C) −70
D) −55
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Unlock Deck
k this deck
9
The resting membrane potential is maintained because

A) potassium ions cannot cross through the cell membrane to the outside.
B) sodium ions cannot cross to the inside of the cell membrane.
C) there is no pressure acting on sodium ions.
D) there is no pressure acting on potassium ions.
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Unlock Deck
k this deck
10
Potassium is said to be at equilibrium during a resting potential because

A) electrostatic pressure forcing it in equals the diffusion pressure forcing it out.
B) diffusion pressure forcing it in equals the electrostatic pressure forcing it out.
C) hydrostatic pressure forcing it in equals the electrostatic pressure forcing it out.
D) it is equally concentrated inside and outside the cell.
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
11
Changes in the voltage of a cell that vary depending on the strength of stimulation are referred to as

A) action potentials.
B) depolarization.
C) hyperpolarization.
D) graded potentials.
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
12
When an axon is depolarized to approximately ________ millivolts, an action potential is initiated.

A) −55
B) −70
C) 0
D) +30
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k this deck
13
Ion channels for sodium ions open when the membrane is ________ to about ________ millivolts.

A) depolarized; −55
B) polarized; −70
C) charged; +30
D) depolarized; 0
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14
The initiation of an action potential is a consequence of an ________ of ________ ions.

A) influx; potassium
B) efflux; chlorine
C) influx; sodium
D) All of the above are correct
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k this deck
15
During an action potential, the membrane voltage changes from ________ to about ________ millivolts on the inside relative to the outside.

A) −70; 0
B) 0; +50
C) −70; +30
D) −70; +55
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Unlock Deck
k this deck
16
Local anesthetics such as lidocaine work by

A) preventing the release of neurotransmitters signaling pain messages.
B) blocking sodium channels so an action potential cannot occur.
C) preventing cells from receiving signals from pain-transmitting neurons.
D) blocking receptor sites for pain-signaling neurotransmitters.
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
17
Myelin is made up of ________ in the central nervous system.

A) fat cells
B) Schwann cells
C) oligodendrocytes
D) astrocytes
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Unlock Deck
k this deck
18
Myelin is made up of ________ in the peripheral nervous system.

A) fat cells
B) Schwann cells
C) oligodendrocytes
D) astrocytes
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Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
19
Gaps in myelin surrounding an axon are referred to as

A) receptors.
B) demyelination.
C) nodes of Ranvier.
D) synapses.
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Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
20
The total amount of neurotransmitter released during an action potential depends on

A) how much sodium enters the terminal button.
B) how much calcium is ejected from the terminal button.
C) regulatory proteins that contain the neurotransmitter substance.
D) how much calcium enters the terminal button.
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
21
Once released into the synaptic gap, neurotransmitter substances

A) bind to receptor sites on both pre- and postsynaptic sites.
B) are degraded by a breakdown enzyme.
C) are returned to the transmitting cell via reuptake.
D) All of the above are correct
Unlock Deck
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Unlock Deck
k this deck
22
Receptor proteins that directly control either the opening or closing of specific ion channels are referred to as ________ receptors.

A) ionotropic
B) metabotropic
C) postsynaptic
D) presynaptic
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Unlock Deck
k this deck
23
Receptor proteins that indirectly open or close ion channels through the activation of a second messenger are referred to as ________ receptors.

A) ionotropic
B) metabotropic
C) postsynaptic
D) presynaptic
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k this deck
24
Which of the following is an example of a second messenger?

A) Sodium
B) A G-protein
C) Acetylcholine
D) Cyclic adenosine monophosphate
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Unlock Deck
k this deck
25
Proteins on the presynaptic terminal that transport neurotransmitter substances back into the terminal button are referred to as

A) G-proteins.
B) reuptake transporters.
C) autoreceptors.
D) metabotropic receptors.
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Unlock Deck
k this deck
26
Receptors on the presynaptic terminal that regulate neurotransmitter synthesis and storage are referred to as

A) heteroreceptors.
B) autoreceptors.
C) metabotropic receptors.
D) Both a and b are correct
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Unlock Deck
k this deck
27
The main difference between autoreceptors and heteroreceptors is that

A) heteroreceptors are activated by a different neuron and neurotransmitter, whereas autoreceptors are activated by the neuron they regulate.
B) heteroreceptors are postsynaptic, whereas autoreceptors are presynaptic.
C) heteroreceptors are metabotropic, whereas autoreceptors are ionotropic.
D) heteroreceptors are excitatory, whereas autoreceptors are inhibitory.
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Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
28
Which of the following is NOT a criterion for a substance to meet the definition of a neurotransmitter?

A) It must be synthesized and stored in the presynaptic neuron.
B) It must cause a postsynaptic effect after it interacts with a receptor.
C) It must be taken up intact by the transmitting neuron.
D) It must have some mechanism for its degradation or reuptake.
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
29
Otto Loewi received the Nobel Prize in 1936 for his discovery of

A) dopamine.
B) norepinephrine.
C) serotonin.
D) acetylcholine.
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
30
The neurotransmitter that activates all neuromuscular synapses is called

A) norepinephrine.
B) acetylcholine.
C) dopamine.
D) muscarine.
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Unlock Deck
k this deck
31
The neurotransmitter of the mesolimbic system is called

A) norepinephrine.
B) serotonin.
C) adenosine.
D) dopamine.
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Unlock Deck
k this deck
32
The neurotransmitter involved in emotional behavior, arousal, and sleep that is derived from the amino acid tryptophan is called

A) dopamine.
B) norepinephrine.
C) serotonin.
D) acetylcholine.
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
33
The most abundant excitatory neurotransmitter is called

A) GABA.
B) serotonin.
C) norepinephrine.
D) glutamate.
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Unlock Deck
k this deck
34
The glutamate receptor that has been implicated as a mechanism for long-term potentiation is called

A) NMDA.
B) metabotropic.
C) kainate.
D) AMPA.
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Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
35
Alcohol binds to a specific receptor site on the ________ receptor complex.

A) NMDA
B) GABA
C) dopamine
D) norepinephrine
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Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
36
The neurotransmitter that transmits pain signals in the spinal cord is called

A) serotonin.
B) glycine.
C) Substance P.
D) nonrepinephrine.
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
37
Anatomical sections through the brain along the axis from front to back are called ________ sections.

A) coronal
B) horizontal
C) sagittal
D) oblique
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
38
The respiratory center of the brain is located in the

A) medulla.
B) pons.
C) midbrain.
D) cerebellum.
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
39
Damage to the ________ might lead to jerky, uncoordinated movements.

A) medulla
B) pons
C) midbrain
D) cerebellum
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
40
A system of neurons originating deep in the brainstem which controls arousal, consciousness, and alertness is the ________ system.

A) mesolimbic
B) reticular activating
C) striatal
D) somatosensory
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
41
The mesolimbic-cortical system originates in the ________ and projects dopamine containing neurons to the ________.

A) nucleus accumbens; frontal cortex
B) septum; prefrontal cortex
C) ventral tegmental area; frontal cortex
D) ventral tegmental area; nucleus accumbens
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
42
The ________ undergoes considerable degeneration with prolonged periods of stress, schizophrenia, or posttraumatic stress disorder.

A) hypothalamus
B) hippocampus
C) thalamus
D) basal ganglia
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
43
The ventromedial nucleus, lateral nucleus, preoptic nucleus, and paraventricular nucleus are all parts of the

A) hypothalamus.
B) thalamus.
C) basal ganglia.
D) mesolimbic system.
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
44
The ________ controls most sensory input to the cortex and is involved in regulating attention and arousal.

A) hypothalamus
B) basal ganglia
C) medulla
D) thalamus
Unlock Deck
Unlock for access to all 46 flashcards in this deck.
Unlock Deck
k this deck
45
Which of the following is NOT part of the basal ganglia?

A) Caudate nucleus
B) Putamen
C) Substantia nigra
D) Nucleus accumbens
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Unlock Deck
k this deck
46
Which of the following structures of the brain is affected by Parkinson's disease?

A) Thalamus
B) Substantia nigra
C) Nucleus accumbens
D) Hippocampus
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Unlock Deck
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