Deck 30: Treatment of Prostate Disease and Erectile Dysfunction

Question 1

All of the following are adverse reactions linked to the administration of a₁-adrenergic antagonists except _____.

A)postural hypotension
B)reflex bradycardia
C)weakness
D)fatigue

Answer 1

reflex bradycardia

Question 2

Which of the following is an example of an antiandrogen?

A)Sildenafil
B)Tamsulosin
C)Dutasteride
D)Alprostadil

Answer 2

Dutasteride

Question 3

An inflamed or infected prostate gland is termed _____.

A)prostatomegaly
B)prostatitis
C)adenoprostitis
D)prostatodynia

Answer 3

prostatitis

Question 4

ED is managed by the administration of drugs that promote _____.

A)engorgement
B)prevention of the loss of erection
C)relaxation and contraction of the smooth muscle in the testes
D)decreasing blood supply to penile muscle

Question 5

It may take up to _____ for finasteride to achieve therapeutic effects.

A)2 weeks
B)6 weeks
C)2 months
D)12 months

Question 6

What is the first line of therapy for BPH?

A)Beta blocker drug therapy
B)5b-Reductase inhibitor drug therapy plus watchful eye on symptoms
C)Alpha blocker drug therapy
D)Watchful eye on symptoms and level of discomfort of symptoms

Question 7

Why are alpha blockers typically dosed daily?

A)Longer half-life allows for daily dosing.
B)It is easier to remember if taken once daily.
C)Bioavailability is decreased when taken more than once a day.
D)It is metabolized faster when taken once a day.

Question 8

What is the typical time frame of alpha blockers to show improvement of symptoms for BPH?

A)6 weeks
B)4 month
C)2 weeks
D)1 week

Question 9

The risk for developing benign prostatic hyperplasia (BPH)increases with _____.

A)obesity
B)hypertension
C)age
D)stress

Question 10

Drugs currently marketed for the treatment of ED are _____.

A)phosphodiesterase (PDE)inhibitors
B)PSA protein vasodilators
C)prostaglandin E analogues
D)phosphodiesterase (PDE)inhibitors and prostaglandin E analogues

Question 11

Which two classes of drugs are used to manage symptoms of BPH?

A)Alpha blockers and 5b-reductase inhibitors
B)5a-Reductase inhibitors and beta blockers
C)a-Adrenergic antagonists and 5a-reductase inhibitors
D)Alpha blockers and beta blockers

Question 12

What test can be conducted to determine if levels of the prostate specific antigen (PSA)protein are elevated?

A)Testosterone hormone level
B)PSA test
C)BPH blockage test
D)Prostate antibody count test

Question 13

Which of the following is not a benefit of a₁-adrenergic antagonists for the treatment of BPH?

A)Relaxation of the prostate gland
B)Increase in urethral resistance
C)Improvement in flow of urine
D)Relaxation of smooth muscle of the bladder neck

Question 14

Coadministration of vardenafil and _____ must be done with caution.

A)glyburide
B)aspirin
C)doxazosin
D)alcohol

Question 15

Which of the following is not a symptom of an enlarged prostate?

A)Weak or slow stream upon urination
B)Less and less urge to urinate
C)Urinary infections
D)Kidney damage

Question 16

Which of the following explains why alpha blockers would be useful for drug therapy of BPH?

A)Alpha blockers antagonize alpha receptors,causing smooth muscle of the prostate and bladder to relax,improving urine flow.
B)Administration of alpha blockers causes prostate muscle to constrict,allowing for easier control of the flow of urine.
C)Alpha blockers act as agonists on alpha receptors,causing smooth muscle relaxation,which improves urethral resistance.
D)Alpha blockers block the normal alpha response,constricting urethral resistance,which allows better control over the flow of urine.

Question 17

In addition to BPH,finasteride can also be used to treat _____.

A)erectile dysfunction (ED)
B)decreased testosterone levels
C)male pattern baldness
D)urinary urgency

Question 18

Why should nitrates be used cautiously in conjunction with PDE inhibitors?

A)Nitrates increase vasodilation to a dangerous level.
B)PDE inhibitors decrease effectiveness of nitrates.
C)Nitrates increase vasoconstriction to a dangerous level.
D)Nitrates prohibit PDE inhibitors from being metabolized.

Question 19

When symptoms of BPH are severe,_____ may be indicated.

A)medication
B)hormone injections
C)vasectomy
D)surgery

Question 20

Which of the following is not a cause of ED?

A)Hyperlipidemia
B)Alcoholism
C)Hypotension
D)Depression

Question 21

MATCHING
Match each of the following trade names with its corresponding generic name.
a.Terazosin
b.Finasteride
c.Tamsulosin
d.Vardenafil
e.Alprostadil
Muse

Question 22

MATCHING
Match each of the following trade names with its corresponding generic name.
a.Terazosin
b.Finasteride
c.Tamsulosin
d.Vardenafil
e.Alprostadil
Hytrin

Question 23

Which of the following herbal remedies helps promote a healthy prostate?

A)Yarrow
B)St.John's wort
C)Saw palmetto
D)Melatonin

Question 24

MATCHING
Match each of the following trade names with its corresponding generic name.
a.Terazosin
b.Finasteride
c.Tamsulosin
d.Vardenafil
e.Alprostadil
Flomax

Question 25

Which of the following would have an increased effectiveness when treating ED?

A)Alprostadil urethral insert
B)Alprostadil tablet
C)Vardenafil IV injection
D)Alprostadil IM injection

Question 26

Why should grapefruit juice be used cautiously while taking PDE inhibitors?

A)Both use the same mechanism of metabolism.
B)Grapefruit juice potentiates the effects of the drug.
C)When taken together,grapefruit juice inactivates the drug.
D)The combination causes an unsafe drop in blood pressure.

Question 27

Alprostadil is a naturally occurring prostaglandin E₁ (PGE₁)and is present in all of the following locations except the _____.

A)seminal vesicles
B)cavernous tissues of males
C)placenta of the fetus
D)prostate gland

Question 28

MATCHING
Match each of the following trade names with its corresponding generic name.
a.Terazosin
b.Finasteride
c.Tamsulosin
d.Vardenafil
e.Alprostadil
Levitra

Question 29

MATCHING
Match each of the following trade names with its corresponding generic name.
a.Terazosin
b.Finasteride
c.Tamsulosin
d.Vardenafil
e.Alprostadil
Proscar

Question 30

Alprostadil is formulated for _____.

A)oral administration
B)intraurethral insertion
C)intravenous (IV)injection
D)intramuscular (IM)injection