Deck 35: Treatment of Bacterial Infection

Question 1

Fluoroquinolones are not formulated for which route of administration?

A)Oral
B)Parenteral
C)Topical
D)Ophthalmic

Answer 1

Topical

Question 2

All of the following drugs are agents that act to inhibit bacterial protein synthesis except _____.

A)aminoglycosides
B)nitroimidazoles
C)tetracyclines
D)oxazolidinones

Answer 2

nitroimidazoles

Question 3

Cephalosporins are formulated for all of the following routes of administration except _____.

A)oral
B)topical
C)intramuscular
D)intravenous

Answer 3

topical

Question 4

How are fluoroquinolones able to fight infections?

A)They inhibit bacterial DNA synthesis by binding to the enzyme kinase.
B)They inhibit kinase,which allows DNA strands to supercoil,inhibiting bacterial replication.
C)They allow DNA strands to uncoil by inhibiting DNA gyrase,which inhibits bacterial replication.
D)They inhibit bacterial DNA synthesis by inhibiting the enzyme DNA gyrase.

Question 5

What is one of the most serious adverse reactions linked to aminoglycoside use?

A)Ototoxicity
B)Neurotoxicity
C)Hepatotoxicity
D)Increased glucose levels

Question 6

Macrolide anti-infectives are used primarily for the treatment of _____.

A)upper respiratory infections (URIs)
B)lower respiratory infections
C)skin infections
D)bronchial infections

Question 7

Gentamicin would be effective for treating all of the following except _____.

A)aerobic gram-negative bacilli
B)staphylococci
C)streptococci
D)mycobacteria

Question 8

First-generation cephalosporins are most effective against what type of bacteria?

A)Gram-positive,aerobic bacteria
B)Gram-negative,aerobic bacteria
C)Gram-positive,anaerobic bacteria
D)Gram-negative,anaerobic bacteria

Question 9

Sulfonamides are used in conjunction with _____ to treat various upper respiratory,urinary tract,and skin infections and AIDS-related pneumonia.

A)vancomycin
B)Retrovir
C)trimethoprim
D)penicillin

Question 10

Which of the following aminoglycosides is given orally to reduce bacteria in the bowel prior to colorectal surgery?

A)Tobramycin
B)Neomycin
C)Streptomycin
D)Kanamycin

Question 11

What advice should the pharmacist give the patient who has just been prescribed penicillin?

A)No problem with gastrointestinal (GI)side effects
B)No allergies to worry about
C)May decrease the effect of oral contraceptives
D)Hunger increases during the treatment

Question 12

Which of the following drugs is not a b-lactam antibiotic?

A)Amoxicillin
B)Cefuroxime
C)Azithromycin
D)Meropenem

Question 13

Which of the following drugs is not a b-lactamase inhibitor?

A)Clavulanic acid
B)Sulbactam
C)Aztreonam
D)Tazobactam

Question 14

Which one of the following would probably be prescribed to treat Lyme's disease?

A)Azithromycin
B)Tetracycline
C)Cefepime
D)Levofloxacin

Question 15

Which of the following cephalosporins could be used to treat bone and joint infections?

A)Ceftazidime
B)Cefaclor
C)Cefuroxime
D)Cephalexin

Question 16

_____ works by inhibiting the synthesis of RNA in bacteria?

A)Rifampin
B)Cephalexin
C)Penicillin
D)Ciprofloxacin

Question 17

Why would inhibiting the synthesis of ribonucleic acid (RNA)help bacteria to stop replicating?

A)This is where the genetic code is stored.If the code cannot be stored,bacteria cannot replicate.
B)It stops bacteria from producing the necessary regulatory proteins to replicate.
C)It inhibits reverse transcriptase,transamidase,and other bacteria-associated enzymes.
D)It inhibits a cell's ability to transfer genetic codes.Without this ability,bacteria cannot replicate.

Question 18

What is the difference between a penicillin and a carbapenem?

A)The b-lactam ring
B)The sulfur-containing ring-like structure
C)The fusion with a penem ring
D)Carbapenem are not inactivated by penicillinase

Question 19

Which of the following would be prescribed for the treatment of gram-positive bacterial pneumonia and skin structure infections?

A)Telithromycin
B)Linezolid
C)Zosyn
D)Merrem

Question 20

_____ factors are not important for the effective treatment of bacterial infections.

A)Host
B)Social
C)Bacterial
D)Drug

Question 21

MATCHING
Match each of the following drugs with its classification.
a.Sulfonamide
b.Miscellaneous
c.Ketolide
d.Tetracycline
e.Fluoroquinolone
f.Penicillin
g.Macrolide
Doxycycline

Question 22

Which anti-infective would be prescribed to a 2-year-old child with impetigo?

A)Cefuroxime
B)Mupirocin
C)Gentamycin
D)Minocycline

Question 23

Multidrug resistance is only a problem in the hospital setting.

Question 24

MATCHING
Match each of the following drugs with its classification.
a.Sulfonamide
b.Miscellaneous
c.Ketolide
d.Tetracycline
e.Fluoroquinolone
f.Penicillin
g.Macrolide
Sulfisoxazole

Question 25

A patient in the process of cleaning out her medicine cabinet found an old prescription vial of tetracycline antibiotic that expired 3 months earlier.She calls the pharmacy and asks if the medication is still good to use even though expired.What advice should she be given?

A)Outdated tetracycline becomes toxic;discard it.
B)Call your physician to find out what to do.
C)The drug is still good for 6 months after the expiration date.
D)Both B and C are correct.

Question 26

_____ has a limited use because of increased ability to create toxicity,especially in neonates.

A)Clindamycin
B)Metronidazole
C)Doxycycline
D)Chloramphenicol

Question 27

Infectious disease is no longer a leading cause of morbidity or mortality throughout the world.

Question 28

MATCHING
Match each of the following drugs with its classification.
a.Sulfonamide
b.Miscellaneous
c.Ketolide
d.Tetracycline
e.Fluoroquinolone
f.Penicillin
g.Macrolide
Dicloxacillin

Question 29

Vancomycin is the only glycopeptide antibiotic available in the United States and Canada.

Question 30

All anti-infectives are natural substances produced by one organism that is capable of destroying or inhibiting the growth of bacteria.

Question 31

MATCHING
Match each of the following drugs with its classification.
a.Sulfonamide
b.Miscellaneous
c.Ketolide
d.Tetracycline
e.Fluoroquinolone
f.Penicillin
g.Macrolide
Levofloxacin

Question 32

MATCHING
Match each of the following drugs with its classification.
a.Sulfonamide
b.Miscellaneous
c.Ketolide
d.Tetracycline
e.Fluoroquinolone
f.Penicillin
g.Macrolide
Telithromycin

Question 33

_____ would be prescribed for the treatment of tuberculosis (TB).

A)Isoniazid
B)Metronidazole
C)Tetracycline
D)Ciprofloxacin

Question 34

Microbial resistance is the ability of bacteria to overcome the effects of an antibiotic.

Question 35

MATCHING
Match each of the following drugs with its classification.
a.Sulfonamide
b.Miscellaneous
c.Ketolide
d.Tetracycline
e.Fluoroquinolone
f.Penicillin
g.Macrolide
Clindamycin

Question 36

MATCHING
Match each of the following drugs with its classification.
a.Sulfonamide
b.Miscellaneous
c.Ketolide
d.Tetracycline
e.Fluoroquinolone
f.Penicillin
g.Macrolide
Azithromycin