Deck 36: Treatment of Viral Infections

Question 1

Why is it important to initiate drug therapy within a certain time period after exposure to a virus or onset of symptoms?

A)A virus is able to replicate at an increased speed within the first 12 hours,so it's important to try to stop it before then.
B)Severity of the infection and symptoms are reduced only when drug therapy is initiated within 1 to 2 days.
C)If the patient is given antivirals within the first 24 hours,the immune system can make enough antibodies to fight the virus.
D)Initiation of antiviral drug therapy is not as important as is getting enough rest when symptoms begin.

Answer 1

Severity of the infection and symptoms are reduced only when drug therapy is initiated within 1 to 2 days.

Question 2

Which of the following factors will not influence the outcome of antiviral therapy?

A)Virus's ability to remain dormant in host
B)Timing of drug therapy initiation
C)Antiviral drug regimen
D)Ability of the virus to penetrate the PNS

Answer 2

Ability of the virus to penetrate the PNS

Question 3

MATCHING
Match each of the following drugs with its corresponding class.
a.Interferon
b.NNRTI
c.PI
d.NRTI
e.Neuraminidase inhibitor
Didanosine

Answer 3

D

Question 4

_____ would be prescribed for the treatment of H1N1 and H3N3 strains of influenza,but some strains may be resistant.

A)Rimantadine
B)Oseltamivir
C)Penciclovir
D)Telbivudine

Question 5

HIV attacks _____and weakens the immune system.

A)CD4 monocytes
B)CD4 T lymphocytes
C)CD2 T lymphocytes
D)CD2 monocytes

Question 6

All of the following are classes of antiretrovirals except _____.

A)nucleoside reverse transcriptase inhibitors (NRTIs)
B)protease inhibitors (PIs)
C)acyclic phosphonate nucleotide analogue
D)fusion inhibitors

Question 7

Efavirenz is teratogenic and classified in Pregnancy Category _____.

A)B
B)C
C)D
D)X

Question 8

The FDA requires the manufacturer of _____ to provide a black box warning in the package labeling regarding reports of fatal and nonfatal intracranial hemorrhage.

A)acyclovir
B)tipranavir
C)saquinavir
D)lopinavir

Question 9

____ has an increased oral absorption when compared to acyclovir and can be prescribed in the treatment of HSV1.

A)Ganciclovir
B)Oseltamivir
C)Trifluridine
D)Valacyclovir

Question 10

The mechanism of action of which of the following drugs used to treat respiratory syncytial virus (RSV)is not completely understood,but it is believed that the drug increases the mutation rate of the virus,leading to a growing number of viruses unable to replicate?

A)Ribavirin
B)Foscarnet
C)Acyclovir
D)Penciclovir

Question 11

MATCHING
Match each of the following drugs with its corresponding class.
a.Interferon
b.NNRTI
c.PI
d.NRTI
e.Neuraminidase inhibitor
PEG-intron

Question 12

The only drug in the fusion inhibitor class is _____.

A)abacavir
B)enfuvirtide
C)fosamprenavir
D)efavirenz

Question 13

Abacavir is an ingredient in the triple antiretroviral therapy that combines it with zidovudine and _____.

A)didanosine
B)lamivudine
C)emtricitabine
D)saquinavir

Question 14

Which drug is not U.S.Food and Drug Administration (FDA)approved for herpes infections but is commonly prescribed for its treatment?

A)Valacyclovir
B)Cidofovir
C)Acyclovir
D)Foscarnet

Question 15

MATCHING
Match each of the following drugs with its corresponding class.
a.Interferon
b.NNRTI
c.PI
d.NRTI
e.Neuraminidase inhibitor
Atazanavir

Question 16

AIDs "cocktails" are made up of _____ or more medications.

A)1 to 2
B)2 to 3
C)3 or more
D)none of the above

Question 17

A good choice of medication therapy for patients with HIV and hepatitis B virus (HBV)coinfections is _____.

A)stavudine
B)emtricitabine
C)didanosine
D)lamivudine

Question 18

_____ is associated with fatal liver toxicity and the FDA has required changes in the package labeling to warn of this adverse effect.

A)Nevirapine
B)Efavirenz
C)Delavirdine
D)Fosamprenavir

Question 19

Despite persistent education worldwide about preventing the spread of acquired immunodeficiency syndrome (AIDS),what may be a cause of increased cases?

A)Translating the importance to other countries has proven difficult because of language barriers.
B)New strains of AIDS have developed because of increased global travel,proving it difficult to contain and fight.
C)Lack of customary standards of living across the world varies widely,leaving the doors open to the development of AIDS.
D)Cases have actually begun to decline,so education has had a vast impact.

Question 20

_____ would be prescribed in the treatment of influenza A.

A)Amantadine
B)Rifampin
C)Lamivudine
D)Acyclovir

Question 21

Interferons are classified as antiviral agents.

Question 22

MATCHING
Match each of the following drugs with its corresponding class.
a.Interferon
b.NNRTI
c.PI
d.NRTI
e.Neuraminidase inhibitor
Nevirapine

Question 23

Antiviral medications are effective against all viruses.

Question 24

Antivirals are not virucidal;they are virustatic.

Question 25

Antiretroviral therapy is a life-long commitment and requires strict adherence to treatment regimens.

Question 26

There are eight steps in the human immunodeficiency virus (HIV)life cycle.

Question 27

MATCHING
Match each of the following drugs with its corresponding class.
a.Interferon
b.NNRTI
c.PI
d.NRTI
e.Neuraminidase inhibitor
Zanamivir