Deck 11: Treatment of Alzheimers Disease

Question 1

Which drug may slow the progression of Alzheimer's disease if administered early enough?

A)Memantine
B)Donepezil
C)Galantamine
D)Rivastigmine

Answer 1

Memantine

Question 2

MATCHING
Match the following trade and generic drug names.
a.Memantine
b.Donepezil
c.Rivastigmine
d.Galantamine
Aricept

Answer 2

B

Question 3

Which of the following conditions is sometimes comorbid with Alzheimer's disease and can speed its progression as a result of its effects on the parasympathetic system?

A)High blood pressure
B)Parkinson's disease
C)Diabetes
D)Dementia

Answer 3

Parkinson's disease

Question 4

Which of the following is a modifiable risk for Alzheimer's disease?

A)Alcohol consumption
B)Smoking
C)Obesity
D)Add weight training to exercise regimen

Question 5

MATCHING
Match the following trade and generic drug names.
a.Memantine
b.Donepezil
c.Rivastigmine
d.Galantamine
Exelon

Question 6

In what stage of Alzheimer's disease may a person become confused and wander,unable to find their way back?

A)Pre-Alzheimer's stage
B)Early stage
C)Moderate stage
D)Late stage

Question 7

_____ could be added to the diet of those with Alzheimer's and heart disease to help decrease the progression of Alzheimer's disease.

A)Flaxseed
B)Olive oil
C)Fiber
D)St.John's wort

Question 8

Which drug can be used as an AChE inhibitor and also slightly increase glutamate activity?

A)Galantamine
B)Donepezil
C)Memantine
D)Rivastigmine

Question 9

Alzheimer's disease causes damage to the _____,the part of the brain that is involved in memory.

A)cerebellum
B)hippocampus
C)medulla
D)thalamus

Question 10

Which of the following is not a normal part of the aging process?

A)Urinary incontinence
B)Aching joints
C)Dementia
D)Minor forgetfulness

Question 11

How do acetylcholinesterase (AChE)inhibitors help treat Alzheimer's disease?

A)They help form a protective lining around muscarinic receptors to only allow binding of ACh.
B)They increase levels of ACh by inhibiting AChE.
C)They help protect any remaining cognition and memory by antagonizing the receptors involved in memory.
D)They decrease levels of ACh by allowing AChE to metabolize ACh,thereby reducing the levels in the brain.

Question 12

The neurotransmitter that plays a significant role in Alzheimer's disease is _____.

A)dopamine
B)norepinephrine
C)ACh
D)serotonin

Question 13

MATCHING
Match the following trade and generic drug names.
a.Memantine
b.Donepezil
c.Rivastigmine
d.Galantamine
Namenda

Question 14

In the future,which of the following vitamins could possibly be used to prevent Alzheimer's disease after adequate studies have been completed and it has been proven effective?

A)A
B)B6
C)D
D)E

Question 15

Reduced function of the _____ receptors is responsible for impaired memory.

A)dopamine
B)adrenergic
C)muscarinic
D)nicotinic

Question 16

MATCHING
Match the following trade and generic drug names.
a.Memantine
b.Donepezil
c.Rivastigmine
d.Galantamine
Reminyl

Question 17

How does Alzheimer's disease develop?

A)Cholinergic nerve cells die in the brain,decreasing the ability to absorb,process,and use information.
B)The hypothalamus becomes blocked by beta amyloids and twisted fibers,blocking transmission signals.
C)Adrenergic nerves become blocked by plaques and tangles,blocking transmission between the neurons.
D)The frontal cortex begins to shrink,losing its ability to think and function.

Question 18

Which of the following is used to block the actions of glutamate to help protect further damage to the neuron?

A)Donepezil
B)Rivastigmine
C)Galantamine
D)Memantine

Question 19

What role do the CLU and CRI genes play in the development of Alzheimer's disease?

A)They allow for transmission through tangles in the brain.
B)They help clear plaques out of the brain.
C)They allow acetylcholine (Ach)to bind to receptors in the brain.
D)They prevent the onset of Alzheimer's disease.

Question 20

_____ is a neurodegenerative disease that causes memory loss,behavioral changes,and immobility.

A)Dementia
B)Multiple sclerosis
C)Cerebrovascular accident
D)Alzheimer's disease