Deck 14: Treatment of Muscle Spasms

Question 1

Which of the following is used to treat a rare adverse reaction to general anesthesia?

A)Dantrolene
B)Diazepam
C)Cyclobenzaprine
D)Metaxalone

Answer 1

Dantrolene

Question 2

MATCHING
Match the following drugs with their classes.
a.Benzodiazepine
b.Antihistamine
c.Peripheral acting drug for the treatment of spasticity
d.GABAergic drug
e.a-Adrenergic agonist
Diazepam

Answer 2

A

Question 3

The effectiveness of baclofen is augmented by administering the drug _____.

A)intravenously
B)orally
C)intrathecally
D)intramuscularly

Answer 3

intrathecally

Question 4

MATCHING
Match the following drugs with their classes.
a.Benzodiazepine
b.Antihistamine
c.Peripheral acting drug for the treatment of spasticity
d.GABAergic drug
e.a-Adrenergic agonist
Cyproheptadine

Question 5

One of the mechanisms of action for centrally acting skeletal muscle relaxants is to _____.

A)increase ACh
B)block a₂-receptors
C)increase GABA actions
D)increase glutamate

Question 6

Which of the following drugs binds to alpha receptors to help diminish painful muscle spasms?

A)Orphenadrine
B)Tizanidine
C)Carisoprodol
D)Cyclobenzaprine

Question 7

Which of the following is not one of the four phases to the development of spasticity?

A)Decreased muscle contractility
B)Weak muscle tone and decreased reflex activity
C)Decreased reflex excitability
D)Contracted muscles

Question 8

The combination of skeletal muscle relaxants and alcohol is an example of _____ effects because they both cause drowsiness.

A)synergistic
B)therapeutic
C)additive
D)potentiation

Question 9

Which of the following appropriately characterizes a theory regarding spasticity development?

A)Decrease in glutamate activity,which allows for an increase in excitatory messages
B)Decrease in reflexes from overstimulation at the neuromuscular junction
C)Death of synapses,creating increased stretching of the muscle
D)Formation of new synapses as a result of neurons branching out from the spinal cord

Question 10

Which of the following warning labels should be placed on a prescription for methocarbamol?

A)May discolor urine.
B)Store in the refrigerator.
C)Protect from light.
D)May be habit forming.

Question 11

Which of the following can be used to treat muscle spasms associated with sprains?

A)Dantrolene
B)Cyproheptadine
C)Metaxalone
D)Diazepam

Question 12

People who have _____ exhibit predominantly negative symptoms of spasticity.

A)muscle strain
B)amyotrophic lateral sclerosis (ALS)
C)multiple sclerosis (MS)
D)hypertonia

Question 13

MATCHING
Match the following drugs with their classes.
a.Benzodiazepine
b.Antihistamine
c.Peripheral acting drug for the treatment of spasticity
d.GABAergic drug
e.a-Adrenergic agonist
Tizanidine

Question 14

Which of the following is not true about the use of botulinum toxin for the treatment of spasticity?

A)It is used to treat abnormal eyelid twitching.
B)Its onset can take up to 7 days.
C)It is injected into the neuromuscular junction.
D)Repeat injections should be administered no sooner than 3 months.

Question 15

Drugs used in the treatment of spasticity are grouped according to _____.

A)when they were discovered
B)their generic name
C)their ability to block ACh
D)their site of action

Question 16

MATCHING
Match the following drugs with their classes.
a.Benzodiazepine
b.Antihistamine
c.Peripheral acting drug for the treatment of spasticity
d.GABAergic drug
e.a-Adrenergic agonist
Dantrolene

Question 17

Why would decreasing glutamate levels help treat ALS?

A)It decreases the flow of calcium into motor neurons,decreasing spasticity.
B)It allows acetylcholine (Ach)to bind to the receptors,decreasing glutamate activity.
C)Glutamate is the main inhibitory neurotransmitter,so decreasing its levels would benefit ALS symptoms.
D)It enhances the actions of GABA,screening out unnecessary sensory messages coming from the environment.

Question 18

MATCHING
Match the following drugs with their classes.
a.Benzodiazepine
b.Antihistamine
c.Peripheral acting drug for the treatment of spasticity
d.GABAergic drug
e.a-Adrenergic agonist
Baclofen

Question 19

Which of the following can be used as supportive therapy for tetanus?

A)Tizanidine
B)Baclofen
C)Ibuprofen
D)Orphenadrine

Question 20

When carisoprodol is combined with codeine,the combination makes it a control Schedule _____ substance.

A)II
B)III
C)IV
D)V

Question 21

Match the following trade names with their generic name.
a.Baclofen
b.Cyclobenzaprine
c.Metaxalone
d.Methocarbamol
e.Carisoprodol
Skelaxin

Question 22

Match the following trade names with their generic name.
a.Baclofen
b.Cyclobenzaprine
c.Metaxalone
d.Methocarbamol
e.Carisoprodol
Soma

Question 23

The goal of most drug treatments for spasticity is to reduce the positive symptoms.

Question 24

Match the following trade names with their generic name.
a.Baclofen
b.Cyclobenzaprine
c.Metaxalone
d.Methocarbamol
e.Carisoprodol
Robaxin

Question 25

Any condition that can damage the brain or spinal cord can cause decreased muscle contractility.

Question 26

Clonus is voluntary rhythmic contractions of muscles.

Question 27

Match the following trade names with their generic name.
a.Baclofen
b.Cyclobenzaprine
c.Metaxalone
d.Methocarbamol
e.Carisoprodol
Flexeril

Question 28

g-Aminobutyric acid (GABA)is the major excitatory neurotransmitter in the nervous system.

Question 29

Positive symptoms associated with spasticity include reduction in the capacity to make voluntary muscle movements.

Question 30

Match the following trade names with their generic name.
a.Baclofen
b.Cyclobenzaprine
c.Metaxalone
d.Methocarbamol
e.Carisoprodol
Lioresal