Deck 18: The Endocrine System
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Deck 18: The Endocrine System
1
Hormones known as "catecholamines" are
A)lipids.
B)peptides.
C)steroids.
D)derivatives of the amino acid tyrosine.
E)derivatives of reproductive glands.
A)lipids.
B)peptides.
C)steroids.
D)derivatives of the amino acid tyrosine.
E)derivatives of reproductive glands.
D
2
Steroid hormones
A)are proteins.
B)cannot diffuse through cell membranes.
C)bind to receptors in the nucleus of their target cells.
D)remain in circulation for relatively short periods of time.
E)are transported in the blood dissolved in the plasma.
A)are proteins.
B)cannot diffuse through cell membranes.
C)bind to receptors in the nucleus of their target cells.
D)remain in circulation for relatively short periods of time.
E)are transported in the blood dissolved in the plasma.
C
3
A kinase is an enzyme that performs
A)phosphorylation.
B)as a membrane channel.
C)active transport.
D)protein synthesis.
E)as an antibody.
A)phosphorylation.
B)as a membrane channel.
C)active transport.
D)protein synthesis.
E)as an antibody.
A
4
Hormones can operate on the ________ level of organization.
A)cellular
B)tissue
C)organ
D)organismic
E)All of the answers are correct.
A)cellular
B)tissue
C)organ
D)organismic
E)All of the answers are correct.
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5
A simple endocrine reflex involves ________ hormone(s).
A)one
B)two
C)hypothalamic
D)gonadotropic
E)tropic
A)one
B)two
C)hypothalamic
D)gonadotropic
E)tropic
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6
Extracellular membrane receptors are used by which of the following types of hormones?
A)catecholamines
B)peptide hormones
C)eicosanoids
D)thyroid
E)catecholamines,peptide hormones,and eicosanoids
A)catecholamines
B)peptide hormones
C)eicosanoids
D)thyroid
E)catecholamines,peptide hormones,and eicosanoids
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7
Calcium ions serve as messengers,often in combination with the intracellular protein
A)calcitonin.
B)calcitriol.
C)calmodulin.
D)calcium-binding globulin.
E)calcitropin.
A)calcitonin.
B)calcitriol.
C)calmodulin.
D)calcium-binding globulin.
E)calcitropin.
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8
________ are chemical messengers that are released in one tissue and transported in the bloodstream to alter the activities of specific cells in other tissues.
A)Hormones
B)Neuropeptides
C)Neurotransmitters
D)Humoral antibodies
E)Antigens
A)Hormones
B)Neuropeptides
C)Neurotransmitters
D)Humoral antibodies
E)Antigens
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9
Hormones can be divided into different groups based on their chemistry.These categories include
A)peptides.
B)steroids.
C)eicosanoids.
D)amino acid derivatives.
E)All of the answers are correct.
A)peptides.
B)steroids.
C)eicosanoids.
D)amino acid derivatives.
E)All of the answers are correct.
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10
An activated G protein can trigger
A)the production of diacylglycerol.
B)the opening of calcium ion channels in the membrane.
C)the release of calcium ions from intracellular stores.
D)a fall in cAMP levels.
E)All of the answers are correct.
A)the production of diacylglycerol.
B)the opening of calcium ion channels in the membrane.
C)the release of calcium ions from intracellular stores.
D)a fall in cAMP levels.
E)All of the answers are correct.
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11
All of the following are true of the nervous system,except that it doesn't
A)respond rapidly to stimuli.
B)respond specifically to stimuli.
C)communicate by the release of neurotransmitters.
D)respond with motor output.
E)function independently of the endocrine system.
A)respond rapidly to stimuli.
B)respond specifically to stimuli.
C)communicate by the release of neurotransmitters.
D)respond with motor output.
E)function independently of the endocrine system.
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12
When a catecholamine or peptide hormone binds to receptors on the surface of a cell,the
A)hormone receptor complex moves into the cytoplasm.
B)cell membrane becomes depolarized.
C)second messenger appears in the cytoplasm.
D)cell becomes inactive.
E)hormone is transported to the nucleus where it alters the activity of DNA.
A)hormone receptor complex moves into the cytoplasm.
B)cell membrane becomes depolarized.
C)second messenger appears in the cytoplasm.
D)cell becomes inactive.
E)hormone is transported to the nucleus where it alters the activity of DNA.
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13
Peptide hormones are
A)composed of amino acids.
B)produced by the suprarenal glands.
C)derived from the amino acid tyrosine.
D)lipids.
E)chemically related to cholesterol.
A)composed of amino acids.
B)produced by the suprarenal glands.
C)derived from the amino acid tyrosine.
D)lipids.
E)chemically related to cholesterol.
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14
The hypothalamus acts as both a neural and a(n)________ organ.
A)endocrine
B)cardiovascular
C)renal
D)muscular
E)hepatic
A)endocrine
B)cardiovascular
C)renal
D)muscular
E)hepatic
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15
All of the following are true of steroid hormones,except that they
A)are produced by the suprarenal medulla.
B)are derived from cholesterol.
C)are produced by reproductive glands.
D)bind to receptors within the cell.
E)are lipids.
A)are produced by the suprarenal medulla.
B)are derived from cholesterol.
C)are produced by reproductive glands.
D)bind to receptors within the cell.
E)are lipids.
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16
Cells can respond to ________ hormone(s)at the same time.
A)only one
B)a few
C)fifty
D)an unlimited number of
A)only one
B)a few
C)fifty
D)an unlimited number of
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17
Each of the following hormones is an amino acid derivative,except
A)epinephrine.
B)norepinephrine.
C)thyroid hormone.
D)thyroid-stimulating hormone.
E)melatonin.
A)epinephrine.
B)norepinephrine.
C)thyroid hormone.
D)thyroid-stimulating hormone.
E)melatonin.
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18
The functional organization of the nervous system parallels that of the ________ system in many ways.
A)endocrine
B)cardiovascular
C)body
D)muscular
E)hepatic
A)endocrine
B)cardiovascular
C)body
D)muscular
E)hepatic
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19
Which of the following substances activates protein kinases and thus acts as a second messenger?
A)insulin
B)ACTH
C)epinephrine
D)cyclic AMP
E)TSH
A)insulin
B)ACTH
C)epinephrine
D)cyclic AMP
E)TSH
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20
Endocrine cells
A)are a type of nerve cell.
B)release their secretions onto an epithelial surface.
C)release their secretions directly into body fluids.
D)contain few vesicles.
E)are modified connective-tissue cells.
A)are a type of nerve cell.
B)release their secretions onto an epithelial surface.
C)release their secretions directly into body fluids.
D)contain few vesicles.
E)are modified connective-tissue cells.
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21
The primary function of ADH is to
A)increase the amount of sodium lost at the kidneys.
B)decrease the amount of water lost at the kidneys.
C)decrease blood pressure.
D)increase digestive absorption.
E)delay urination.
A)increase the amount of sodium lost at the kidneys.
B)decrease the amount of water lost at the kidneys.
C)decrease blood pressure.
D)increase digestive absorption.
E)delay urination.
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22
Hormone release may be controlled by which of the following factors?
A)blood level of an ion-like potassium
B)blood level of glucose
C)blood level of a hormone
D)nervous stimuli
E)All of the answers are correct.
A)blood level of an ion-like potassium
B)blood level of glucose
C)blood level of a hormone
D)nervous stimuli
E)All of the answers are correct.
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23
The most complex endocrine responses involve the
A)thyroid gland.
B)pancreas.
C)suprarenal glands.
D)hypothalamus.
E)thymus gland.
A)thyroid gland.
B)pancreas.
C)suprarenal glands.
D)hypothalamus.
E)thymus gland.
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24
When adenyl cyclase is activated,
A)ATP is consumed.
B)cAMP is formed.
C)cAMP is broken down.
D)ATP is produced.
E)ATP is consumed and cAMP is formed.
A)ATP is consumed.
B)cAMP is formed.
C)cAMP is broken down.
D)ATP is produced.
E)ATP is consumed and cAMP is formed.
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25
The main action of antidiuretic hormone is:
A)increased water conservation by kidneys
B)stimulate kidney cells to secrete renin
C)increase urine output to remove excess fluid
D)increased blood pressure by increased Na+ reabsorption
E)inhibition of aldosterone
A)increased water conservation by kidneys
B)stimulate kidney cells to secrete renin
C)increase urine output to remove excess fluid
D)increased blood pressure by increased Na+ reabsorption
E)inhibition of aldosterone
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26
The hypophyseal portal system
A)is a blood connection between the hypothalamus to the anterior pituitary.
B)has two capillary plexuses connected by short veins.
C)carries neurosecretions to the anterior lobe of the pituitary.
D)carries ADH and oxytocin.
E)All of the answers are correct.
A)is a blood connection between the hypothalamus to the anterior pituitary.
B)has two capillary plexuses connected by short veins.
C)carries neurosecretions to the anterior lobe of the pituitary.
D)carries ADH and oxytocin.
E)All of the answers are correct.
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27
The hypothalamus controls secretion by the adenohypophysis by
A)direct neural stimulation.
B)indirect osmotic control.
C)secreting releasing and inhibiting factors into a tiny portal system.
D)altering ion concentrations and pH in the anterior pituitary.
E)gap synaptic junctions.
A)direct neural stimulation.
B)indirect osmotic control.
C)secreting releasing and inhibiting factors into a tiny portal system.
D)altering ion concentrations and pH in the anterior pituitary.
E)gap synaptic junctions.
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28
The link between a first messenger and a second messenger in a cell that responds to peptide hormones is usually
A)cAMP.
B)cGMP.
C)adenyl cyclase.
D)a G protein.
E)calcium ion levels.
A)cAMP.
B)cGMP.
C)adenyl cyclase.
D)a G protein.
E)calcium ion levels.
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29
Which of the following hormones is/are water soluble and therefore bind(s)to extracellular receptors?
A)insulin
B)epinephrine
C)cortisol
D)calcitriol
E)insulin and epinephrine
A)insulin
B)epinephrine
C)cortisol
D)calcitriol
E)insulin and epinephrine
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30
After a steroid hormone binds to its receptor to form an active complex,
A)adenyl cyclase is activated.
B)cyclic nucleotides are formed.
C)G proteins are phosphylated.
D)gene transcription is initiated.
E)protein kinases are activated.
A)adenyl cyclase is activated.
B)cyclic nucleotides are formed.
C)G proteins are phosphylated.
D)gene transcription is initiated.
E)protein kinases are activated.
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31
Increased activity of phosphodiesterase in a target cell would decrease its level of
A)testosterone.
B)estrogen.
C)thyroid hormone.
D)cAMP.
E)progesterone.
A)testosterone.
B)estrogen.
C)thyroid hormone.
D)cAMP.
E)progesterone.
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32
Destruction of the supraoptic nucleus of the hypothalamus would have which result?
A)loss of ADH secretion
B)loss of GH secretion
C)loss of melatonin secretion
D)loss of emotional response
E)loss of loss of regulatory factor secretion
A)loss of ADH secretion
B)loss of GH secretion
C)loss of melatonin secretion
D)loss of emotional response
E)loss of loss of regulatory factor secretion
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33
Hormonal actions on cells include those that affect
A)quantities of enzymes.
B)activities of enzymes.
C)synthesis of enzymes.
D)gating of ion channels.
E)All of the answers are correct.
A)quantities of enzymes.
B)activities of enzymes.
C)synthesis of enzymes.
D)gating of ion channels.
E)All of the answers are correct.
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34
If the median eminence of the hypothalamus is destroyed,the hypothalamus would no longer be able to control the secretion of which of the following hormones?
A)TSH
B)ACTH
C)PRL
D)ADH and OXT
E)TSH,ACTH,PRL
A)TSH
B)ACTH
C)PRL
D)ADH and OXT
E)TSH,ACTH,PRL
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35
Neurons of the supraoptic and paraventricular nuclei of the hypothalamus manufacture
A)CRF and GnRH.
B)TSH and FSH.
C)ADH and oxytocin.
D)FSH and PRL.
E)GHIH and GHRH.
A)CRF and GnRH.
B)TSH and FSH.
C)ADH and oxytocin.
D)FSH and PRL.
E)GHIH and GHRH.
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36
Changes in blood osmotic pressure would most affect the secretion of
A)ACTH.
B)ADH.
C)oxytocin.
D)TSH.
E)LH.
A)ACTH.
B)ADH.
C)oxytocin.
D)TSH.
E)LH.
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37
If the adenyl cyclase activity of liver cells were missing,which of these hormones could no longer stimulate release of glucose?
A)insulin
B)glucagon
C)cortisol
D)thyroxine
E)leptin
A)insulin
B)glucagon
C)cortisol
D)thyroxine
E)leptin
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38
Secretory cells of the adenohypophysis release
A)FSH.
B)TSH.
C)ACTH.
D)GH.
E)All of the answers are correct.
A)FSH.
B)TSH.
C)ACTH.
D)GH.
E)All of the answers are correct.
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39
All target cells
A)have hormone receptors.
B)respond to electrical signals.
C)secrete hormones.
D)produce their own hormones.
E)are in the blood.
A)have hormone receptors.
B)respond to electrical signals.
C)secrete hormones.
D)produce their own hormones.
E)are in the blood.
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40
Excess secretion of growth hormone during early development will cause
A)dwarfism.
B)rickets.
C)gigantism.
D)acromegaly.
E)diabetes insipidus.
A)dwarfism.
B)rickets.
C)gigantism.
D)acromegaly.
E)diabetes insipidus.
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41
Which of the following organs contain target cells for oxytocin?
A)prostate
B)ductus deferens
C)mammary glands
D)uterus
E)All of the answers are correct.
A)prostate
B)ductus deferens
C)mammary glands
D)uterus
E)All of the answers are correct.
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42
Growth hormone does all of the following,except that it
A)promotes bone growth.
B)promotes muscle growth.
C)causes fat accumulation within adipocytes.
D)is glucose sparing.
E)promotes amino acid uptake by cells.
A)promotes bone growth.
B)promotes muscle growth.
C)causes fat accumulation within adipocytes.
D)is glucose sparing.
E)promotes amino acid uptake by cells.
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43
Which of the following hormones may lead to acromegaly if hypersecreted after closure of the epiphyseal plates?
A)cortisol
B)parathyroid hormone
C)insulin
D)growth hormone
E)epinephrine
A)cortisol
B)parathyroid hormone
C)insulin
D)growth hormone
E)epinephrine
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44
The pituitary hormone that promotes ovarian secretion of progesterone and testicular secretion of testosterone is
A)TSH.
B)ACTH.
C)FSH.
D)LH.
E)GH.
A)TSH.
B)ACTH.
C)FSH.
D)LH.
E)GH.
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45
The pituitary hormone that triggers the release of thyroid hormone from the thyroid gland is
A)TSH.
B)ACTH.
C)FSH.
D)LH.
E)GH.
A)TSH.
B)ACTH.
C)FSH.
D)LH.
E)GH.
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46
Liver cells respond to growth hormone by releasing hormones called
A)gonadotrophins.
B)prostaglandins.
C)hepatic hormones.
D)somatomedins.
E)glucocorticoids.
A)gonadotrophins.
B)prostaglandins.
C)hepatic hormones.
D)somatomedins.
E)glucocorticoids.
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47
The pituitary hormone that controls the release of glucocorticoids from the suprarenal cortex is
A)TSH.
B)ACTH.
C)FSH.
D)LH.
E)GH.
A)TSH.
B)ACTH.
C)FSH.
D)LH.
E)GH.
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48
The posterior pituitary gland secretes
A)FSH.
B)TSH.
C)ACTH.
D)ADH.
E)MSH.
A)FSH.
B)TSH.
C)ACTH.
D)ADH.
E)MSH.
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49
The pituitary hormone that stimulates cell growth and replication by accelerating protein synthesis is
A)ACTH.
B)MSH.
C)prolactin.
D)insulin.
E)somatotropin.
A)ACTH.
B)MSH.
C)prolactin.
D)insulin.
E)somatotropin.
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50
The pituitary hormone that promotes egg development in ovaries and sperm development in testes is
A)TSH.
B)ACTH.
C)FSH.
D)LH.
E)GH.
A)TSH.
B)ACTH.
C)FSH.
D)LH.
E)GH.
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51
PRL is to ________ as ACTH is to ________.
A)prolactin; corticotropin
B)oxytocin; mammotropin
C)gonadotropin; mammotropin
D)oxytocin; cortisol
A)prolactin; corticotropin
B)oxytocin; mammotropin
C)gonadotropin; mammotropin
D)oxytocin; cortisol
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52
The two lobes of the pituitary gland together produce how many hormones?
A)3
B)5
C)7
D)9
E)16
A)3
B)5
C)7
D)9
E)16
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53
The hormone produced by the pars intermedia of the adenohypophysis during early childhood is
A)FSH.
B)ADH.
C)TSH.
D)MSH.
E)ACTH.
A)FSH.
B)ADH.
C)TSH.
D)MSH.
E)ACTH.
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54
The term used to describe excess production of urine is
A)polyuria.
B)polydipsia.
C)hematuria.
D)glycosuria.
E)diabetes insipidis
A)polyuria.
B)polydipsia.
C)hematuria.
D)glycosuria.
E)diabetes insipidis
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55
After brain surgery,a patient receiving postoperative care in an intensive care unit began to pass large volumes of very dilute urine. The ICU nurse administered a medicine that mimics one of the following hormones.Which one?
A)aldosterone
B)epinephrine
C)renin
D)ADH
E)cortisol
A)aldosterone
B)epinephrine
C)renin
D)ADH
E)cortisol
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56
The pituitary hormone that causes the kidney to reduce water loss is
A)TSH.
B)FSH.
C)MSH.
D)STH.
E)ADH.
A)TSH.
B)FSH.
C)MSH.
D)STH.
E)ADH.
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57
The pituitary hormone that stimulates milk production by the mammary glands is
A)TSH.
B)ACTH.
C)growth hormone.
D)FSH.
E)prolactin.
A)TSH.
B)ACTH.
C)growth hormone.
D)FSH.
E)prolactin.
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58
Melanocyte-stimulating hormone (MSH)is secreted by the human pars intermedia
A)during pregnancy.
B)in very young children.
C)during fetal development.
D)in some disease processes.
E)All of the answers are correct.
A)during pregnancy.
B)in very young children.
C)during fetal development.
D)in some disease processes.
E)All of the answers are correct.
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59
Each of the following hormones is produced by the pars distalis of the adenohypophysis,except
A)FSH.
B)oxytocin.
C)TSH.
D)corticotropin.
E)somatotropin.
A)FSH.
B)oxytocin.
C)TSH.
D)corticotropin.
E)somatotropin.
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60
The hormone oxytocin
A)promotes uterine contractions.
B)is responsible for milk expression from the mammary glands.
C)triggers prostate gland contraction.
D)is produced in the hypothalamus.
E)All of the answers are correct.
A)promotes uterine contractions.
B)is responsible for milk expression from the mammary glands.
C)triggers prostate gland contraction.
D)is produced in the hypothalamus.
E)All of the answers are correct.
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61
The C cells of the thyroid gland produce
A)thyroxine.
B)TSH.
C)calcitonin.
D)PTH.
E)triiodothyronine.
A)thyroxine.
B)TSH.
C)calcitonin.
D)PTH.
E)triiodothyronine.
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62

Figure 18-1 Pituitary Hormones and Their Targets
Use Figure 18-1 to answer the following questions:
Identify the hormone labeled "5."
A)thyroid-releasing hormone
B)thyroid-stimulating hormone
C)thyroxin
D)thyrotropin
E)parathyroid hormone (PTH)
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63
Increased levels of the hormone ________ will lead to increased levels of calcium ion in the blood.
A)thymosin
B)calcitonin
C)PTH
D)aldosterone
E)cortisol
A)thymosin
B)calcitonin
C)PTH
D)aldosterone
E)cortisol
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64
TSH plays a key role in the ________ of thyroid hormones.
A)inhibition
B)synthesis
C)release
D)inhibition and secretion
E)synthesis and release
A)inhibition
B)synthesis
C)release
D)inhibition and secretion
E)synthesis and release
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65
Mental and physical sluggishness and low body temperature may be signs of
A)hyperthyroidism.
B)hypothyroidism.
C)hyperparathyroidism.
D)hypoparathyroidism.
E)diabetes insipidus.
A)hyperthyroidism.
B)hypothyroidism.
C)hyperparathyroidism.
D)hypoparathyroidism.
E)diabetes insipidus.
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66
The control of calcitonin excretion is an example of direct ________ regulation.
A)endocrine
B)pancreatic
C)homeostatic
D)hepatic
E)vascular
A)endocrine
B)pancreatic
C)homeostatic
D)hepatic
E)vascular
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67

Figure 18-1 Pituitary Hormones and Their Targets
Use Figure 18-1 to answer the following questions:
A deficiency of which hormone can lead to diabetes insipidus?
A)3
B)7
C)2
D)8
E)14
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68
Where does the chemical reaction between thyroglobulin and iodine take place?
A)in lysosomes
B)in rough endoplasmic reticulum
C)in the lumen of the thyroid follicle
D)in pinocytotic vesicles
E)in apical microvilli
A)in lysosomes
B)in rough endoplasmic reticulum
C)in the lumen of the thyroid follicle
D)in pinocytotic vesicles
E)in apical microvilli
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69

Figure 18-1 Pituitary Hormones and Their Targets
Use Figure 18-1 to answer the following questions:
Identify the hormone labeled "13."
A)LH
B)progesterone
C)estrogen
D)oxytocin
E)testosterone
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70
Which of the following cells are target cells for the hormone that causes a decrease in blood-calcium concentration?
A)alpha cells
B)osteoclasts
C)osteoblasts
D)C cells
E)All cells in the body,especially cartilage,bone,and muscle cells.
A)alpha cells
B)osteoclasts
C)osteoblasts
D)C cells
E)All cells in the body,especially cartilage,bone,and muscle cells.
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71

Figure 18-1 Pituitary Hormones and Their Targets
Use Figure 18-1 to answer the following questions:
Identify the hormone labeled "1."
A)mineralocorticoid
B)cortisol
C)dopamine
D)corticotropin (ACTH)
E)aldosterone
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72

Figure 18-1 Pituitary Hormones and Their Targets
Use Figure 18-1 to answer the following questions:
Identify the hormone labeled "4."
A)thyroid-releasing hormone
B)thyroid-stimulating hormone
C)thyroxin
D)thyrotropin
E)calcitonin
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73
Which of the following is a known effect of thyroid hormone on peripheral tissues?
A)increased oxygen consumption
B)increased heart rate
C)increased sensitivity to adrenergic stimulation
D)increased body temperature
E)All of the answers are correct.
A)increased oxygen consumption
B)increased heart rate
C)increased sensitivity to adrenergic stimulation
D)increased body temperature
E)All of the answers are correct.
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74
The hormone that may be slowly administered by intravenous drip to accelerate labor and delivery is
A)oxytocin.
B)prolactin.
C)luteinizing hormone.
D)just extra fluids.
E)both oxytocin and luteinizing hormone.
A)oxytocin.
B)prolactin.
C)luteinizing hormone.
D)just extra fluids.
E)both oxytocin and luteinizing hormone.
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75
Inadequate iodine in the diet may lead to
A)hypothyroidism.
B)cretinism.
C)myxedema.
D)high blood levels of TSH.
E)All of the answers are correct.
A)hypothyroidism.
B)cretinism.
C)myxedema.
D)high blood levels of TSH.
E)All of the answers are correct.
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76
Which of the following elements is necessary for the production of thyroid hormone?
A)sodium
B)iodine
C)potassium
D)iron
E)colloid
A)sodium
B)iodine
C)potassium
D)iron
E)colloid
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77
The condition known as hirsutism can result from too
A)much insulin.
B)little TSH.
C)much ACTH.
D)much androgen production.
E)little glucagon.
A)much insulin.
B)little TSH.
C)much ACTH.
D)much androgen production.
E)little glucagon.
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78
A hormone that can lower blood levels of calcium ion is
A)parathyroid hormone.
B)thyroxine.
C)calcitonin.
D)glucagon.
E)oxytocin.
A)parathyroid hormone.
B)thyroxine.
C)calcitonin.
D)glucagon.
E)oxytocin.
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79
Thyroid hormone contains the element
A)fluorine.
B)chlorine.
C)iron.
D)iodine.
E)zinc.
A)fluorine.
B)chlorine.
C)iron.
D)iodine.
E)zinc.
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80
The hormone that plays a pivotal role in setting the metabolic rate and thus impacting body temperature is
A)somatotropin.
B)thyroxine.
C)calcitonin.
D)parathyroid hormone.
E)glucagon.
A)somatotropin.
B)thyroxine.
C)calcitonin.
D)parathyroid hormone.
E)glucagon.
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