Deck 5: Aneuploidy

Question 1

Which assessment findings would indicate the need to test for Edwards syndrome?

A)Hydrocephalus
B)Misshaped nose
C)Cleft palate
D)Cardiac defects
E)Cognitive slowing

Answer 1

Cleft palate
Cardiac defects
Cognitive slowing

Question 2

An analysis of tissues indicates that an aborted fetus had nullisomy.How would the nurse explain this finding to the parents?

A)"Your baby had an additional chromosome that was incompatible with life."
B)"Some of your baby's chromosomes were arranged incorrectly."
C)"Your baby's chromosomes were damaged during fertilization."
D)"Your baby was lacking two chromosomes."

Answer 2

"Your baby was lacking two chromosomes."

Question 3

A woman with Type 1 diabetes is considering becoming pregnant.How should the nurse use research information to establish a plan of care?

A)Discourage the client from considering pregnancy.
B)Make contact with the client frequently for monitoring.
C)Alert the client that few women with diabetes are able to complete pregnancy without serious complications
D)Teach the client about methods of maintaining tight glycemic control.
E)Help the mother understand the need to loosen restrictions on carbohydrate consumption while pregnant.

Answer 3

Make contact with the client frequently for monitoring.
Teach the client about methods of maintaining tight glycemic control.

Question 4

The client has nullisomy.How would the nurse document the equation for this condition?

A)2n+1
B)2n-2
C)2n-1
D)2n+2

Question 5

A client's genetic disorder is thought to be attributable to unbalanced translocation.How would the nurse explain this phenomenon to the client's family?

A)"Portions of your child's chromosomes are not arranged normally."
B)"Aneuploidy has occurred."
C)"Some genetic material is missing."
D)"Duplications of genetic material have occurred."
E)"Your child's cells are missing an entire chromosome."

Question 6

Which assessment findings would the nurse expect in a new female client diagnosed with Turner syndrome?

A)Tall height for age
B)X-ray confirmation of coarctation of the aorta
C)Heavy menstrual periods
D)Heart murmur
E)Multiple bruises

Question 7

A nurse comments that the only aneuploid conditions he has seen in his practice are Patau syndrome,Edwards syndrome,and Down syndrome.What rationale would the genetics specialist suggest?

A)The diagnosis of aneuploidy is made early in the pregnancy,so women whose fetuses demonstrate other conditions are referred to high-risk providers.
B)These are all monosomic conditions,which have a higher survival rate to delivery.
C)The chromosomes affected are small.
D)Spontaneous abortions are rare among fetuses with these conditions.

Question 8

A nurse who works in oncology questions the need to attend an education session on aneuploidy.What rationale would the nurse manager provide?

A)The hospital is offering cross-training to nurses so that they have more job security.
B)Accreditation agencies require cross-specialty education for all nurses.
C)Aneuploidy,transcription,and tumor suppression are related.
D)Many more newborns are being born with precancerous conditions.

Question 9

A nurse who works in a high-risk obstetric practice provides care to women who are carrying fetuses with aneuploidy.The nurse would plan care based on the knowledge that which types of aneuploidy almost always result in fetal demise or spontaneous abortion?

A)Monosomy
B)Trisomy
C)Nullisomy
D)Tetrasomy

Question 10

Which finding would the nurse expect when assessing children who have Klinefelter syndrome?

A)Increased facial hair in males
B)Small breast size in females
C)Decreased testicular size in males
D)Misshapen ears in females

Question 11

The nurse observes that many of the children affected by genetic aneuploidy have defects in cognition and mental function.How would the genetics nurse specialist explain this phenomenon?

A)A decrease in oxygenation through the placenta results in the dysfunction of brain cells.
B)Many of the chromosomes affected by these disorders are involved in the development of the brain and spinal cord.
C)Because of chromosomal alterations,the brain tissues are unable to release the toxins associated with metabolism.
D)Aneuploidy results in slight variations in the fetus's thermal control,and sensitive tissues such as the brain,heart,and liver are damaged.

Question 12

The nurse is aware that physical growth retardation is a common finding in aneuploid conditions.Which assessment findings are generally associated with this growth pattern?

A)Microcephaly
B)Facial malformations
C)Small heart size
D)Compressed rib cage
E)Lack of body hair

Question 13

A 60-year-old man and his 39-year-old wife would like to have children.Which information should the nurse provide concerning the risk for genetic disorders?

A)The sperm of older men is more likely to contain defects of cell division.
B)The sperm of older men has been exposed to more damaging chemicals than that of younger men.
C)At age 39,the woman runs a much higher risk of nondisjunction anomalies than younger women do.
D)Aging in the woman is not considered a risk factor for having children with chromosomal abnormalities.

Question 14

An analysis of aborted tissues reveals that the fetus had an aneuploid condition.The nurse asks the mother if her menstrual periods are generally regular.What is the rationale for this question?

A)Many spontaneous abortions occur before the mother is aware she is pregnant.
B)Menstrual irregularities signal hormone alterations that may cause aneuploidy.
C)Spontaneous abortion often "resets" a woman's hormonal cycle,making periods more regular.
D)Aneuploidy's greatest effects are on the secondary sexual characteristics.