Deck 14: B-Lymphocyte-Activation

Question 1

For each of the descriptions in questions ,select the B cell signaling molecule (A-I)that most closely matches it.
A protein that is the cell surface receptor for Epstein-Barr virus

A)Iga
B)Igb
C)C3b
D)C3d
E)CR2
F)CD19
G)CD81
H)Fyn
I)Syk

Answer 1

CR2

Question 2

For each of descriptions in questions ,select the letter of the Ig isotype (A-E)that most closely matches it.Answers may be used more than once.
An allergic reaction

A)IgM
B)IgD
C)IgG
D)IgE
E)IgA

Answer 2

IgE

Question 3

A child is infected with a virus,mounts antibody responses to a viral protein,and recovers.One year later,the child is exposed to the same type of virus,and mounts a memory response specific to the same viral protein.Which one of the following statements comparing the (primary)antibody response to the viral protein and the memory response a year later is true?

A)The antibodies in primary responses were of highrt affinity for viral protein than those produced in memory responses.
B)The peak blood levels of antibodies during the primary response was higher than in the memory response.
C)T follicular helper (Tfh)were mainly required during the memory response,and not in the primary response.
D)Antibodies specific for the viral protein were only produced by plasma cells in the memory response.
E)In the primary response,mainly IgG was produced,whereas in the memory responses mainly IgM was produced.

Answer 3

In the primary response,mainly IgG was produced,whereas in the memory responses mainly IgM was produced.

Question 4

For each of descriptions in questions ,select the letter of the Ig isotype (A-E)that most closely matches it.Answers may be used more than once.
T cell-independent antigens

A)IgM
B)IgD
C)IgG
D)IgE
E)IgA

Question 5

For each of the descriptions in questions ,select the B cell signaling molecule (A-I)that most closely matches it.
A protein tyrosine kinase homologous to Zap-70,which phosphorylates several adaptor proteins and enzymes

A)Iga
B)Igb
C)C3b
D)C3d
E)CR2
F)CD19
G)CD81
H)Fyn
I)Syk

Question 6

For each of descriptions in questions ,select the letter of the Ig isotype (A-E)that most closely matches it.Answers may be used more than once.
Binds to receptors in the gastrointestinal tract of infants for absorption into the serum

A)IgM
B)IgD
C)IgG
D)IgE
E)IgA

Question 7

For each of descriptions in questions ,select the letter of the Ig isotype (A-E)that most closely matches it.Answers may be used more than once.
Unclear functional role

A)IgM
B)IgD
C)IgG
D)IgE
E)IgA

Question 8

For each of descriptions in questions ,select the letter of the Ig isotype (A-E)that most closely matches it.Answers may be used more than once.
Phagocytosis

A)IgM
B)IgD
C)IgG
D)IgE
E)IgA

Question 9

For each of the descriptions in questions ,select the B cell signaling molecule (A-I)that most closely matches it.
An Src family kinase that phosphorylates ITAMs in the cytoplasmic tails of B cell receptor complex proteins

A)Iga
B)Igb
C)C3b
D)C3d
E)CR2
F)CD19
G)CD81
H)Fyn
I)Syk

Question 10

Which one of the following statements about humoral immune responses is true?

A)Naive B cells are required for initiation of primary responses and memory B cells are required for initiation of secondary responses.
B)Antibody responses to bacterial polysaccharide antigens require CD4+ helper T cells.
C)Heavy chain isotype switching typically occurs in response to bacterial polysaccharide antigens.
D)Affinity maturation does not require T follicular helper T cells.
E)Antibody-secreting cells generated during a humoral immune response live for only a few hours.

Question 11

For each of the descriptions in questions ,select the B cell signaling molecule (A-I)that most closely matches it.
A protein that covalently binds to microbes and serves as a ligand for a coreceptor that enhances B cell responses to antigen

A)Iga
B)Igb
C)C3b
D)C3d
E)CR2
F)CD19
G)CD81
H)Fyn
I)Syk