Deck 17: Antibody-Immunity

Question 1

For each of the following descriptions in questions ,select the Fc receptor (A-G)that best matches it.
Low-affinity Ig receptor on natural killer cells that mediates antibody-dependent cell-mediated cytotoxicity

A)FcgRI (CD64)
B)FcgRIIB (CD32)
C)FcgRIIIA (CD16)
D)FceRI
E)FceRII (CD23)
F)FcaR (CD89)
G)FcRn

Answer 1

FcgRIIIA (CD16)

Question 2

For each of the following descriptions in questions ,select the Fc receptor (A-G)that best matches it.
High-affinity Ig receptor on mast cells important in immediate hypersensitivity reactions

A)FcgRI (CD64)
B)FcgRIIB (CD32)
C)FcgRIIIA (CD16)
D)FceRI
E)FceRII (CD23)
F)FcaR (CD89)
G)FcRn

Answer 2

FceRI

Question 3

For each of the following descriptions in questions ,select the Fc receptor (A-G)that best matches it.
High-affinity Ig receptor on macrophages and neutrophils important for phagocytosis and activation

A)FcgRI (CD64)
B)FcgRIIB (CD32)
C)FcgRIIIA (CD16)
D)FceRI
E)FceRII (CD23)
F)FcaR (CD89)
G)FcRn

Answer 3

FcgRI (CD64)

Question 4

For each of the functions described in questions ,select the complement system protein (A-F)that best matches it.
Generated by factor I-mediated proteolysis,this complement fragment binds to complement receptor 2 (CR2)on B cells and enhances B cell activation.

A)C3b
B)iC3b
C)C3d
D)C5b
E)C5a

Question 5

For each of the functions described in questions ,select the complement system protein (A-F)that best matches it.
Produced by C3 convertases,this opsonin promotes phagocytosis of microbes.

A)C3b
B)iC3b
C)C3d
D)C5b
E)C5a

Question 6

Which of the following anatomic regions is normally protected from pathogens only by humoral immune responses and not by cell-mediated immune responses?

A)Skin
B)Intestinal lumen
C)Intestinal epithelium
D)Central nervous system
E)Spleen

Question 7

For each of the following descriptions in questions ,select the Fc receptor (A-G)that best matches it.
Ig receptor on B cells that mediates feedback inhibition

A)FcgRI (CD64)
B)FcgRIIB (CD32)
C)FcgRIIIA (CD16)
D)FceRI
E)FceRII (CD23)
F)FcaR (CD89)
G)FcRn

Question 8

For each of the functions described in questions ,select the complement system protein (A-F)that best matches it.
This complement fragment is a chemoattractant for neutrophils.

A)C3b
B)iC3b
C)C3d
D)C5b
E)C5a

Question 9

For each of the functions described in questions ,select the complement system protein (A-F)that best matches it.
This complement fragment is a component of the membrane attack complex.

A)C3b
B)iC3b
C)C3d
D)C5b
E)C5a

Question 10

For each of the functions described in questions ,select the complement system protein (A-F)that best matches it.
Generated by factor I-mediated proteolysis,this opsonizing complement fragment binds to CR3 on phagocytes.

A)C3b
B)iC3b
C)C3d
D)C5b
E)C5a