Deck 18: Antibodies

Question 1

Match each description in questions with the appropriate lettered term (A-I).
A region of an antibody molecule that permits bivalent binding of antibodies to pairs of surface epitopes varying in distance from one another

A)Conformational determinant
B)Linear determinant
C)Neoantigenic determinant
D)Hinge region
E)Immun complex
F)Fab
G)Fc
H)Tail piece
I)Hapten

Answer 1

Hinge region

Question 2

Match each of the descriptions in questions with the correct lettered antibody isotype (A-E).(Answers may be used more than once. )
The isotype found predominantly in mucosal secretions

A)IgA
B)IgD
C)IgE
D)IgG
E)IgM

Answer 2

IgA

Question 3

Match each description in questions with the appropriate lettered term (A-I).
A three-dimensional shape,formed by a portion of a macromolecule,to which an antibody binds

A)Conformational determinant
B)Linear determinant
C)Neoantigenic determinant
D)Hinge region
E)Immun complex
F)Fab
G)Fc
H)Tail piece
I)Hapten

Answer 3

Conformational determinant

Question 4

Match each of the descriptions in questions with the correct lettered antibody isotype (A-E).(Answers may be used more than once. )
The secreted form of this isotype forms pentamers around a J chain

A)IgA
B)IgD
C)IgE
D)IgG
E)IgM

Question 5

Match each description in questions with the appropriate lettered term (A-I).
A small chemical group recognized by an antibody that is attached to a larger macromolecule

A)Conformational determinant
B)Linear determinant
C)Neoantigenic determinant
D)Hinge region
E)Immun complex
F)Fab
G)Fc
H)Tail piece
I)Hapten

Question 6

Match each description in questions with the appropriate lettered term (A-I).
A proteolytic fragment of an antibody molecule that contains an intact antigen-binding site

A)Conformational determinant
B)Linear determinant
C)Neoantigenic determinant
D)Hinge region
E)Immun complex
F)Fab
G)Fc
H)Tail piece
I)Hapten

Question 7

Match each of the descriptions in questions with the correct lettered antibody isotype (A-E).(Answers may be used more than once. )
The isotype most closely associated with immediate hypersensitivity (allergic)disease

A)IgA
B)IgD
C)IgE
D)IgG
E)IgM

Question 8

Match each description in questions with the appropriate lettered term (A-I).
The proteolytic fragment of an antibody molecule that contains the heavy chain constant region

A)Conformational determinant
B)Linear determinant
C)Neoantigenic determinant
D)Hinge region
E)Immun complex
F)Fab
G)Fc
H)Tail piece
I)Hapten

Question 9

Match each of the descriptions in questions with the correct lettered antibody isotype (A-E).(Answers may be used more than once. )
The isotype only found in membrane-bound form on naive B cells

A)IgA
B)IgD
C)IgE
D)IgG
E)IgM

Question 10

Match each of the descriptions in questions with the correct lettered antibody isotype (A-E).(Answers may be used more than once. )
The most abundant Ig isotype in the blood

A)IgA
B)IgD
C)IgE
D)IgG
E)IgM