Nester's Microbiology 8th Edition by Denise Anderson,Sarah Salm,Deborah Allen

Exercise 2

Mutant strains of Helicobacter pylori that lack the ability to produce urease fail to cause infection when they are swallowed. Infection occurs, however, if a tube is used to introduce them directly into the layer of mucus that overlies the stomach epithelium. What does this imply about the role of urease in the bacterium's pathogenicity?