Becker's World of the Cell 9th Edition by Lewis Kleinsmith, Jeff Hardin, Gregory Paul Bertoni

Exercise 1

Triplets or Sextuplets In his Nobel Prize lecture in 1962, Francis Crick pointed out that while the pioneering experiments he performed with Barnett, Brenner, and Watts-Tobin suggested that the DNA "code" is a triplet, their experiments did not rule out the possibility that the code could require six or nine bases.
(a)Assuming the code is a triplet, what effect would adding or removing six or nine bases have on the reading frame of a piece of DNA
(b)If the code actually were a sextuplet, how would addition of three, six, or nine nucleotides affect the reading frame of a piece of DNA