
Essential Genetics 6th Edition by Daniel Hartl
Edition 6ISBN: 978-1449686482
Essential Genetics 6th Edition by Daniel Hartl
Edition 6ISBN: 978-1449686482 Exercise 20
Two E. coli genes, A and B , are known from mapping experiments to be very close to each other. A deletion mutation is isolated that eliminates the activity of both A and B. Neither the A nor the B protein can be found in the mutant, but a novel protein is isolated in which the amino-terminal 30 amino acids are identical to those of the B gene product and the carboxyl terminal 30 amino acids are identical to those of the A gene product.
(a) With regard to the 5' ?3' orientation of the nontranscribed DNA strand, is the order of the genes A B or B A ?
(b) Can you make any inference about the number of bases deleted?
(a) With regard to the 5' ?3' orientation of the nontranscribed DNA strand, is the order of the genes A B or B A ?
(b) Can you make any inference about the number of bases deleted?
Explanation
(a)From the given data, Gene A and B are...
Essential Genetics 6th Edition by Daniel Hartl
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