Essential Genetics 6th Edition by Daniel Hartl

Exercise 1

A condition called nonsyndromic recessive auditory neuropathy results in deafness. One form is caused by a recessive autosomal gene. The frequency of affected individuals due to the mutant gene in one population is 0.002. Assuming Hardy- Weinberg equilibrium, what is the expected incidence of the disorder among the offspring of matings in which both parents are heterozygous carriers?