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Molecular Biology of the Gene 7th Edition by Richard Losick, James Watson, Michael Levine, Tamara Baker, Alexander Gann
Edition 7ISBN: 9780321762436Molecular Biology of the Gene 7th Edition by Richard Losick, James Watson, Michael Levine, Tamara Baker, Alexander Gann
Edition 7ISBN: 9780321762436 Exercise 6
The antiviral drug Acyclovir (structure pictured below) is used to treat infections caused by double-stranded DNA viruses such as herpes simplex virus. Acyclovir acts at the level of DNA synthesis.
A. Acyclovir functions as the analog of what deoxynucleoside?
B. Acyclovir cannot be incorporated into the DNA unless it is modified by a virally encoded kinase. Explain why the activity of a kinase is required for Acyclovir to be incorporated during DNA synthesis.
A. Acyclovir functions as the analog of what deoxynucleoside?
B. Acyclovir cannot be incorporated into the DNA unless it is modified by a virally encoded kinase. Explain why the activity of a kinase is required for Acyclovir to be incorporated during DNA synthesis.
Explanation
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Acyclovir is an antiviral drug. It funct...
Molecular Biology of the Gene 7th Edition by Richard Losick, James Watson, Michael Levine, Tamara Baker, Alexander Gann
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