
Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
Edition 2ISBN: 9780130819086
Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
Edition 2ISBN: 9780130819086 Exercise 14
Consider the data given in the table on the temperature changes in a 10,000-l fermenter,
which includes the heat-up and cool-down periods. Use the values for the Arrhenius parame-
ters given in Problem 10.8 and assume an initial spore concentration of
and a vitamin
concentration of 30 mg/l.
a. What is the probability of a successful sterilization?
b. What fraction of the vitamin remains undegraded?
c. What fraction of the vitamin is degraded in the sterilization period?
d. What fraction of the vitamin is degraded in the heat-up and cool-down periods?
e. What is the fraction of spores deactivated in the heat-up and cool-down cycles?
which includes the heat-up and cool-down periods. Use the values for the Arrhenius parame-
ters given in Problem 10.8 and assume an initial spore concentration of

concentration of 30 mg/l.

a. What is the probability of a successful sterilization?
b. What fraction of the vitamin remains undegraded?
c. What fraction of the vitamin is degraded in the sterilization period?
d. What fraction of the vitamin is degraded in the heat-up and cool-down periods?
e. What is the fraction of spores deactivated in the heat-up and cool-down cycles?
Explanation
According to the given data:
The number ...
Bioprocess Engineering 2nd Edition by Fikret Kargi,Michael Shuler
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